Technology Process of 2-[2,5-dimethoxy-4-(pentylsulfanyl)phenyl]-N-methylethanamine
There total 7 articles about 2-[2,5-dimethoxy-4-(pentylsulfanyl)phenyl]-N-methylethanamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate; boron trifluoride diethyl etherate;
In
tetrahydrofuran;
1.) RT, 1 h, 2.) reflux, 3 h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 97 percent / EtONa / ethanol / 5 h / Heating
2: 1.) HCl / 1.) dioxane, water, 65 deg C, 10 min, 2.) 60 to 65 deg C, 30 min
3: 86 percent / dimethylformamide / 5.5 h / 40 - 95 °C
4: 100 percent / AlCl3, LiAlH4 / diethyl ether; tetrahydrofuran / 6 h / Heating
5: 1.) acetic anhydride / 1.) 60 deg C, 2 h, 2.) RT, 24 h
6: NaBH4, BF3*OEt2 / tetrahydrofuran / 1.) RT, 1 h, 2.) reflux, 3 h
With
hydrogenchloride; sodium tetrahydroborate; lithium aluminium tetrahydride; aluminium trichloride; boron trifluoride diethyl etherate; sodium ethanolate; acetic anhydride;
In
tetrahydrofuran; diethyl ether; ethanol; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 97 percent / EtONa / ethanol / 5 h / Heating
2: 1.) HCl / 1.) dioxane, water, 65 deg C, 10 min, 2.) 60 to 65 deg C, 30 min
3: 86 percent / dimethylformamide / 5.5 h / 40 - 95 °C
4: 100 percent / AlCl3, LiAlH4 / diethyl ether; tetrahydrofuran / 6 h / Heating
5: 1.) acetic anhydride / 1.) 60 deg C, 2 h, 2.) RT, 24 h
6: NaBH4, BF3*OEt2 / tetrahydrofuran / 1.) RT, 1 h, 2.) reflux, 3 h
With
hydrogenchloride; sodium tetrahydroborate; lithium aluminium tetrahydride; aluminium trichloride; boron trifluoride diethyl etherate; sodium ethanolate; acetic anhydride;
In
tetrahydrofuran; diethyl ether; ethanol; N,N-dimethyl-formamide;
