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11-Hydroxydodecanoic acid

Base Information
  • Chemical Name:11-Hydroxydodecanoic acid
  • CAS No.:32459-66-8
  • Molecular Formula:C12H24 O3
  • Molecular Weight:216.321
  • Hs Code.:2918199090
  • DSSTox Substance ID:DTXSID00954211
  • Nikkaji Number:J262.046D
  • Wikidata:Q27146452
  • Metabolomics Workbench ID:1371
  • ChEMBL ID:CHEMBL4291425
  • Mol file:32459-66-8.mol
11-Hydroxydodecanoic acid

Synonyms:11-hydroxydodecanoic acid

Suppliers and Price of 11-Hydroxydodecanoic acid
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 11-HydroxylauricAcid
  • 5mg
  • $ 155.00
  • Medical Isotopes, Inc.
  • 11-HydroxylauricAcid
  • 25 mg
  • $ 2400.00
  • American Custom Chemicals Corporation
  • 11-HYDROXY LAURIC ACID 95.00%
  • 5MG
  • $ 385.00
Total 6 raw suppliers
Chemical Property of 11-Hydroxydodecanoic acid
Chemical Property:
  • Vapor Pressure:2.12E-06mmHg at 25°C 
  • Boiling Point:353.2°Cat760mmHg 
  • Flash Point:181.6°C 
  • PSA:57.53000 
  • Density:0.987g/cm3 
  • LogP:2.96270 
  • Storage Temp.:-20°C Freezer, Under inert atmosphere 
  • Solubility.:DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) 
  • XLogP3:3.3
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:10
  • Exact Mass:216.17254462
  • Heavy Atom Count:15
  • Complexity:157
Purity/Quality:

97% *data from raw suppliers

11-HydroxylauricAcid *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(CCCCCCCCCC(=O)O)O
  • General Description 11-Hydroxy lauric acid (also known as 11-hydroxydodecanoic acid) is a hydroxylated derivative of lauric acid, produced through enzymatic hydroxylation catalyzed by cytochrome P450 enzymes such as CYP119 and P450 BM3 mutants. Its formation is enhanced by mutations that improve substrate binding, electron transfer efficiency, or redox partner interactions, as demonstrated in studies involving CYP119 (T214V/D77R) and P450 BM3 (W1046A). These modifications optimize catalytic activity, enabling efficient hydroxylation at the 11-position of lauric acid, with potential applications in biocatalysis and biotechnology.
Technology Process of 11-Hydroxydodecanoic acid

There total 7 articles about 11-Hydroxydodecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With 2,3,4,5,6-pentahydroxy-hexanal; cytochrome b5; glucose dehydrogenase from Bacillus megaterium; human cytochrome P450 monooxygenase; rat cytochrome P450 reductase; 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine; NADPH; superoxide dismutase; catalase from bovine liver; In aq. phosphate buffer; dimethyl sulfoxide; at 30 ℃; pH=7.5; Enzymatic reaction;
DOI:10.1016/j.abb.2019.108216
Guidance literature:
With 2,3,4,5,6-pentahydroxy-hexanal; cytochrome b5; glucose dehydrogenase from Bacillus megaterium; rabbit cytochrome P450 monooxygenase; rat cytochrome P450 reductase; 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine; NADPH; superoxide dismutase; catalase from bovine liver; In aq. phosphate buffer; dimethyl sulfoxide; at 30 ℃; pH=7.5; Enzymatic reaction;
DOI:10.1016/j.abb.2019.108216
Guidance literature:
With potassium phosphate; wild-type CYP119; dihydrogen peroxide; In ethanol; water; at 50 ℃; pH=7.4; regiospecific reaction; Enzymatic reaction;
DOI:10.1002/anie.200901485
upstream raw materials:

lauric acid

Sodium laurate

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