(ω-4)-Hydroxylauric acid

Base Information

• Chemical Name: (ω-4)-Hydroxylauric acid
• CAS No.: 16899-07-3
• Molecular Formula: C₁₂H₂₄O₃
• Molecular Weight: 216.321
• Mol file: 16899-07-3.mol

Synonyms:(ω-4)-Hydroxylauric acid;8-Hydroxydodecanoic acid;8-Hydroxylauric acid;4-Hydroxydodecanoic acid

Chemical Property of (ω-4)-Hydroxylauric acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (ω-4)-Hydroxylauric acid

There total 1 articles about (ω-4)-Hydroxylauric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

lauric acid (143-07-7) → 12-hydroxydodecanoic acid (505-95-3) + (±)-4-hydroxydodecanoic acid (16899-07-3) + 11-Hydroxylauric acid (32459-66-8)

Guidance literature:

With 2,3,4,5,6-pentahydroxy-hexanal; cytochrome b5; glucose dehydrogenase from Bacillus megaterium; rabbit cytochrome P₄₅₀ monooxygenase; rat cytochrome P₄₅₀ reductase; 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine; NADPH; superoxide dismutase; catalase from bovine liver; In aq. phosphate buffer; dimethyl sulfoxide; at 30 ℃; pH=7.5; Enzymatic reaction;

DOI:10.1016/j.abb.2019.108216

Reference yield: 40.0%

(±)-4-hydroxydodecanoic acid (16899-07-3) + benzyl bromide (100-39-0) → benzyl 4-hydroxydodecanoate

Guidance literature:

In N,N-dimethyl-formamide; at 20 ℃; for 2h; Inert atmosphere;

Reference yield:

(±)-4-hydroxydodecanoic acid (16899-07-3) → (R)-4-dodecanolide (69830-91-7,2305-05-7) + 5(S)-octyl-2(3H)-dihydrofuranone (69830-92-8,2305-05-7)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 1h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

upstream raw materials:

lauric acid

Downstream raw materials:

gamma-dodecalactone

(R)-4-dodecanolide

5(S)-octyl-2(3H)-dihydrofuranone