1,1':3',1''-Terphenyl, 4-chloro-5'-phenyl-

Base Information

• Chemical Name: 1,1':3',1''-Terphenyl, 4-chloro-5'-phenyl-
• CAS No.: 116941-51-6
• Molecular Formula: C24H17Cl
• Molecular Weight: 340.852
• Mol file: 116941-51-6.mol

Synonyms:1,1':3',1''-TERPHENYL, 4-CHLORO-5'-PHENYL-;

Chemical Property of 1,1':3',1''-Terphenyl, 4-chloro-5'-phenyl-

Chemical Property:

• Melting Point: 141.0 to 145.0 °C
• Boiling Point: 489.9±14.0 °C(Predicted)
• PSA: 0.00000
• Density: 1.146±0.06 g/cm3(Predicted)
• LogP: 7.34100

Purity/Quality:

97% ^*data from raw suppliers

4-Chloro-5''-phenyl-1,1'':3'',1''''-terphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,1':3',1''-Terphenyl, 4-chloro-5'-phenyl-

There total 19 articles about 1,1':3',1''-Terphenyl, 4-chloro-5'-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-bromo-3-(4-chlorophenyl)acrylaldehyde (13301-77-4) + (E,Z)-2-benzoyl-3-phenylbut-2-enenitrile (35491-57-7) → 4-chloro-5′-phenyl-1,1′:3′,1″-terphenyl (116941-51-6)

Guidance literature:

3-bromo-3-(4-chlorophenyl)acrylaldehyde; (E,Z)-2-benzoyl-3-phenylbut-2-enenitrile; With 2-phenyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; caesium carbonate; In 1,4-dioxane; at 20 ℃; Inert atmosphere; Schlenk technique;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,4-dioxane; at 20 ℃; for 1.5h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.6b03306

Reference yield: 76.0%

p-chlorocinnamic acid (1615-02-7,940-62-5) + (E,Z)-2-benzoyl-3-phenylbut-2-enenitrile (35491-57-7) → 4-chloro-5′-phenyl-1,1′:3′,1″-terphenyl (116941-51-6)

Guidance literature:

p-chlorocinnamic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 2h; Schlenk technique; Inert atmosphere;

(E,Z)-2-benzoyl-3-phenylbut-2-enenitrile; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 20 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.joc.8b01740

Reference yield: 74.0%

dypnone (495-45-4) + para-chloroacetophenone (99-91-2) → 4-chloro-5′-phenyl-1,1′:3′,1″-terphenyl (116941-51-6)

Guidance literature:

With tetrachlorosilane; ethanol; at 25 ℃; for 17h;

DOI:10.1016/S0040-4039(96)02470-7

upstream raw materials:

[6-(4-chloro-phenyl)-2-hydroxy-2,4-diphenyl-cyclohex-3-enyl]-phenyl ketone

acetic anhydride

dypnone

para-chloroacetophenone