(1'S,3R,5R)-5-benzyloxy-3-hydroxyhexanoic acid 2'-hydroxy-1',2',2'-triphenylethyl ester

Base Information

Chemical Name:(1'S,3R,5R)-5-benzyloxy-3-hydroxyhexanoic acid 2'-hydroxy-1',2',2'-triphenylethyl ester
CAS No.:115460-93-0
Molecular Formula:C₃₃H₃₄O₅
Molecular Weight:510.63
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1'S,3R,5R)-5-benzyloxy-3-hydroxyhexanoic acid 2'-hydroxy-1',2',2'-triphenylethyl ester

Chemical Property:

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Technology Process of (1'S,3R,5R)-5-benzyloxy-3-hydroxyhexanoic acid 2'-hydroxy-1',2',2'-triphenylethyl ester

There total 3 articles about (1'S,3R,5R)-5-benzyloxy-3-hydroxyhexanoic acid 2'-hydroxy-1',2',2'-triphenylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-39-0
benzyl bromide

: 115460-93-0
(1'S,3R,5R)-5-benzyloxy-3-hydroxyhexanoic acid 2'-hydroxy-1',2',2'-triphenylethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 71 percent / AgNO₃, NaOH / diethyl ether / 3 h / Heating

2: 85 percent / 1M DIBAL / CH₂Cl₂; hexane / 4 h / -78 °C

With sodium hydroxide; diisobutylaluminium hydride; silver nitrate; In diethyl ether; hexane; dichloromethane;

Reference yield:

: 115460-90-7
ethyl (R)-(3-benzyloxybutyrate)

: 115460-93-0
(1'S,3R,5R)-5-benzyloxy-3-hydroxyhexanoic acid 2'-hydroxy-1',2',2'-triphenylethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / 1M DIBAL / CH₂Cl₂; hexane / 4 h / -78 °C

With diisobutylaluminium hydride; In hexane; dichloromethane;