6-(4-Methoxyphenyl)[1,2,4]triazolo[4,3-b]pyridazine

Base Information

Chemical Name:6-(4-Methoxyphenyl)[1,2,4]triazolo[4,3-b]pyridazine
CAS No.:117979-38-1
Molecular Formula:C12H10N4O
Molecular Weight:226.238
Hs Code.:
DSSTox Substance ID:DTXSID50558465
Wikidata:Q82440782
Mol file:117979-38-1.mol

Synonyms:117979-38-1;SCHEMBL2887160;6-(4-Methoxyphenyl)[1,2,4]triazolo[4,3-b]pyridazine;DTXSID50558465

Suppliers and Price of 6-(4-Methoxyphenyl)[1,2,4]triazolo[4,3-b]pyridazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-(4-Methoxyphenyl)[1,2,4]triazolo[4,3-b]pyridazine

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:226.08546096
Heavy Atom Count:17
Complexity:255

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NN3C=NN=C3C=C2

Technology Process of 6-(4-Methoxyphenyl)[1,2,4]triazolo[4,3-b]pyridazine

There total 4 articles about 6-(4-Methoxyphenyl)[1,2,4]triazolo[4,3-b]pyridazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 117979-31-4
(E,E)-N-<3-(dimethylamino)-1-(4-methoxyphenyl)-2-propenylidene>-4H-1,2,4-triazol-4-amine

: 117979-38-1
6-(4-methoxyphenyl)-1,2,4-triazolo<4,3-b>pyridazine

Guidance literature:: In acetic acid; for 6.5h; Heating;

Reference yield: 27.0%

: 624-84-0
formic acid hydrazide

: 58059-31-7
3-chloro-6-(4-methoxyphenyl)pyridazine

: 117979-38-1
6-(4-methoxyphenyl)-1,2,4-triazolo<4,3-b>pyridazine

Guidance literature:: With triethylamine hydrochloride; In xylene; for 2h; Heating / reflux;

Reference yield:

: 100-06-1
1-(4-methoxyphenyl)ethanone

: 117979-38-1
6-(4-methoxyphenyl)-1,2,4-triazolo<4,3-b>pyridazine

Guidance literature:: Multi-step reaction with 3 steps

1: 94 percent / p-toluenesulfonic acid / toluene / 4.5 h / Heating

2: 95 percent / tetrahydrofuran / 96 h / 23 °C

3: 85 percent / acetic acid / 6.5 h / Heating

With toluene-4-sulfonic acid; In tetrahydrofuran; acetic acid; toluene;