2-Propanone, 1-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-

Base Information

• Chemical Name: 2-Propanone, 1-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-
• CAS No.: 118171-02-1
• Molecular Formula: C19H24O2Si
• Molecular Weight: 312.484
• DSSTox Substance ID: DTXSID60391385
• Nikkaji Number: J2.523.066C
• Wikidata: Q82188813
• Mol file: 118171-02-1.mol

Synonyms:118171-02-1;2-Propanone, 1-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-;SCHEMBL7336991;DTXSID60391385;1-(tert-Butyldiphenylsiloxy)acetone

Chemical Property of 2-Propanone, 1-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 312.154556538
• Heavy Atom Count: 22
• Complexity: 342

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)CO[Si](C1=CC=CC=C1)(C2=CC=CC=C2)C(C)(C)C

Technology Process of 2-Propanone, 1-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-

There total 6 articles about 2-Propanone, 1-[[(1,1-dimethylethyl)diphenylsilyl]oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

hydroxy-2-propanone (116-09-6) + tert-butylchlorodiphenylsilane (58479-61-1) → 1-(tert-butyldiphenylsilyloxy)-2-propanone (118171-02-1)

Guidance literature:

With 1H-imidazole; dmap; In N,N-dimethyl-formamide; at 0 ℃; for 10h;

DOI:10.1021/jo00032a021

Reference yield: 91.0%

3-(tert-butyldiphenylsilyloxy)prop-1-ene (136787-49-0) → 1-(tert-butyldiphenylsilyloxy)-2-propanone (118171-02-1)

Guidance literature:

With chromium(VI) oxide; palladium dichloride; In water; acetonitrile; at 20 - 60 ℃; for 12h;

DOI:10.1016/j.tet.2014.05.022

Reference yield: 88.0%

1-((tert-butyldiphenylsilyl)oxy)propan-2-ol (125803-68-1) → 1-(tert-butyldiphenylsilyloxy)-2-propanone (118171-02-1)

Guidance literature:

With acetic anhydride; pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 1h; Molecular sieve;

DOI:10.1002/chem.201200694

upstream raw materials:

hydroxy-2-propanone

tert-butylchlorodiphenylsilane

tert-butyl(diphenyl)(2-propynyloxy)silane

2-[(tert-butyldiphenylsilyl)oxy]ethanol

Downstream raw materials:

(E)-ethyl 4-(tert-butyl-diphenyl-silanyloxy)-3-methyl-but-2-enoate

1-(tert-butyldiphenylsiloxy)-2-cyclopropylidenepropane

1-<(tert-butyldiphenylsilyl)oxy>-2-hydroxy-2-methyl-3-pentanone

1-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-2-trimethylsilanyloxy-pentan-3-one