Technology Process of C9H5ClF2O3
There total 7 articles about C9H5ClF2O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.67 h
1.2: 5 h / 20 °C
2.1: aminosulfonic acid; sodium chlorite / water; acetonitrile / 1 h / 20 °C
3.1: thionyl chloride / 1 h / 84 °C
4.1: triethylamine / toluene / 1.17 h / 20 °C
5.1: hydrogen; 10% Pd/C / ethyl acetate; ethanol / 48 h / 20 °C
6.1: thionyl chloride / 1 h / 85 °C
With
sodium chlorite; thionyl chloride; 10% Pd/C; aminosulfonic acid; hydrogen; sodium hydride; triethylamine;
In
ethanol; water; ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile; mineral oil;
DOI:10.1002/cmdc.201200319
- Guidance literature:
-
Multi-step reaction with 5 steps
1: aminosulfonic acid; sodium chlorite / water; acetonitrile / 1 h / 20 °C
2: thionyl chloride / 1 h / 84 °C
3: triethylamine / toluene / 1.17 h / 20 °C
4: hydrogen; 10% Pd/C / ethyl acetate; ethanol / 48 h / 20 °C
5: thionyl chloride / 1 h / 85 °C
With
sodium chlorite; thionyl chloride; 10% Pd/C; aminosulfonic acid; hydrogen; triethylamine;
In
ethanol; water; ethyl acetate; toluene; acetonitrile;
DOI:10.1002/cmdc.201200319
- Guidance literature:
-
Multi-step reaction with 2 steps
1: hydrogen; 10% Pd/C / ethyl acetate; ethanol / 48 h / 20 °C
2: thionyl chloride / 1 h / 85 °C
With
thionyl chloride; 10% Pd/C; hydrogen;
In
ethanol; ethyl acetate;
DOI:10.1002/cmdc.201200319
