4-Hydroxy-2-nonenal, (+)-

Base Information

• Chemical Name: 4-Hydroxy-2-nonenal, (+)-
• CAS No.: 119008-09-2
• Molecular Formula: C9H16O2
• UNII: 654CDG6AXX
• Nikkaji Number: J1.909.726I,J683.877D
• Wikidata: Q27126367
• Metabolomics Workbench ID: 60311
• Mol file: 119008-09-2.mol

Synonyms:4S-Hydroxy-2E-nonenal;4-Hydroxy-2-nonenal, (+)-;S-HNE;UNII-654CDG6AXX;654CDG6AXX;2-Nonenal, 4-hydroxy-, (2E,4S)-;CHEBI:58967;(2E,4S)-4-hydroxynon-2-enal;119008-09-2;Epitope ID:119071;(+)-4-hydroxy-2-nonenal;(4S)-4-Hydroxy-2-nonenal;4(S)-HNE;SCHEMBL2890600;Q27126367

Chemical Property of 4-Hydroxy-2-nonenal, (+)-

Chemical Property:

• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 156.115029749
• Heavy Atom Count: 11
• Complexity: 119

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCC(C=CC=O)O
• Isomeric SMILES: CCCCC[C@@H](/C=C/C=O)O

Technology Process of 4-Hydroxy-2-nonenal, (+)-

There total 1 articles about 4-Hydroxy-2-nonenal, (+)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + icomucret (54845-95-3,73945-47-8,83603-31-0) → methyl (5Z,8Z,13E)-11,12-trans-epoxy-15-hydroxy-5,8,13-eicosatrienoate + (5Z,8Z,11Z,13E,15S)-15-hydroxy-5,8,11,13-eicosatetraenoic acid methyl ester (70946-44-0) + (2E,4S)-4-hydroxy-2-nonenal (119008-09-2)

Guidance literature:

icomucret; With ammonium iron (II) sulfate; ethylenediaminetetraacetic acid; dihydrogen peroxide; phosphate buffer; In chloroform; for 1h; pH=7.4;

diazomethane; In diethyl ether; ethyl acetate; for 0.25h;

DOI:10.1016/j.chemphyslip.2006.02.015

Reference yield:

(S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine (22751-68-4,60508-97-6,60509-62-8,70749-06-3,118628-68-5) + (2E,4S)-4-hydroxy-2-nonenal (119008-09-2) → (E)-(S)-1-((4S,5S)-1,3-Dimethyl-4,5-diphenyl-imidazolidin-2-yl)-oct-1-en-3-ol (128946-66-7)

Guidance literature:

With 4 A molecular sieve; In dichloromethane; Yield given;

upstream raw materials:

diazomethane

icomucret

Downstream raw materials:

(E)-(S)-1-((4S,5S)-1,3-Dimethyl-4,5-diphenyl-imidazolidin-2-yl)-oct-1-en-3-ol