N-{3-cyano-6-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-4-phenylpyridin-2-yl}formimidic ethyl ester

Base Information

• Chemical Name: N-{3-cyano-6-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-4-phenylpyridin-2-yl}formimidic ethyl ester
• CAS No.: 750632-18-9
• Molecular Formula: C₃₆H₂₇N₇O₂
• Molecular Weight: 589.656
• Mol file: 750632-18-9.mol

Synonyms:

Chemical Property of N-{3-cyano-6-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-4-phenylpyridin-2-yl}formimidic ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-{3-cyano-6-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-4-phenylpyridin-2-yl}formimidic ethyl ester

There total 3 articles about N-{3-cyano-6-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-4-phenylpyridin-2-yl}formimidic ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

orthoformic acid triethyl ester (122-51-0) + 2-amino-6-{4-[5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl]phenyl}-4-phenylnicotinonitrile (750632-17-8) → N-{3-cyano-6-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-4-phenylpyridin-2-yl}formimidic ethyl ester (750632-18-9)

Guidance literature:

With acetic anhydride; for 5h; Heating;

DOI:10.1515/znb-2003-1212

Reference yield:

benzaldehyde (100-52-7) → N-{3-cyano-6-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-4-phenylpyridin-2-yl}formimidic ethyl ester (750632-18-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 77 percent / aq. KOH / ethanol / 3 h

2: 62 percent / CH₃COONH₄ / ethanol / 10 h / Heating

3: 86 percent / Ac₂O / 5 h / Heating

With potassium hydroxide; ammonium acetate; acetic anhydride; In ethanol;

DOI:10.1515/znb-2003-1212

Reference yield:

3-[4-acetylphenyl]-2-phenyl-5-phenylhydrazono-3,5-dihydroimidazol-4-one → N-{3-cyano-6-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-4-phenylpyridin-2-yl}formimidic ethyl ester (750632-18-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 77 percent / aq. KOH / ethanol / 3 h

2: 62 percent / CH₃COONH₄ / ethanol / 10 h / Heating

3: 86 percent / Ac₂O / 5 h / Heating

With potassium hydroxide; ammonium acetate; acetic anhydride; In ethanol;

DOI:10.1515/znb-2003-1212

upstream raw materials:

orthoformic acid triethyl ester

2-amino-6-{4-[5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl]phenyl}-4-phenylnicotinonitrile

benzaldehyde

Downstream raw materials:

7-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-5-phenyl-3H-1,4,8,9,10a-pentaazaphenanthren-2-one