7-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-5-phenyl-3H-1,4,8,9,10a-pentaazaphenanthren-2-one

Base Information

• Chemical Name: 7-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-5-phenyl-3H-1,4,8,9,10a-pentaazaphenanthren-2-one
• CAS No.: 750632-33-8
• Molecular Formula: C₃₆H₂₅N₉O₂
• Molecular Weight: 615.654
• Mol file: 750632-33-8.mol

Synonyms:

Chemical Property of 7-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-5-phenyl-3H-1,4,8,9,10a-pentaazaphenanthren-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-5-phenyl-3H-1,4,8,9,10a-pentaazaphenanthren-2-one

There total 6 articles about 7-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-5-phenyl-3H-1,4,8,9,10a-pentaazaphenanthren-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

chloroacetyl chloride (79-04-9) + 3-[4-(3-amino-4-imino-5-phenyl-3,4-dihydropyrido[2,3-d]pyrimidin-7-yl)phenyl]-2-phenyl-5-phenylhydrazono-3,5-dihydroimidazol-4-one (750632-19-0) → 7-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-5-phenyl-3H-1,4,8,9,10a-pentaazaphenanthren-2-one (750632-33-8)

Guidance literature:

In 1,4-dioxane; at 20 ℃;

DOI:10.1515/znb-2003-1212

Reference yield:

benzaldehyde (100-52-7) → 7-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-5-phenyl-3H-1,4,8,9,10a-pentaazaphenanthren-2-one (750632-33-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 77 percent / aq. KOH / ethanol / 3 h

2: 62 percent / CH₃COONH₄ / ethanol / 10 h / Heating

3: 86 percent / Ac₂O / 5 h / Heating

4: 71 percent / hydrazine hydrate / benzene / 0.75 h

5: 66 percent / dioxane / 20 °C

With potassium hydroxide; ammonium acetate; acetic anhydride; hydrazine hydrate; In 1,4-dioxane; ethanol; benzene;

DOI:10.1515/znb-2003-1212

Reference yield:

3-[4-acetylphenyl]-2-phenyl-5-phenylhydrazono-3,5-dihydroimidazol-4-one → 7-[4-(5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl)phenyl]-5-phenyl-3H-1,4,8,9,10a-pentaazaphenanthren-2-one (750632-33-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 77 percent / aq. KOH / ethanol / 3 h

2: 62 percent / CH₃COONH₄ / ethanol / 10 h / Heating

3: 86 percent / Ac₂O / 5 h / Heating

4: 71 percent / hydrazine hydrate / benzene / 0.75 h

5: 66 percent / dioxane / 20 °C

With potassium hydroxide; ammonium acetate; acetic anhydride; hydrazine hydrate; In 1,4-dioxane; ethanol; benzene;

DOI:10.1515/znb-2003-1212

upstream raw materials:

chloroacetyl chloride

3-[4-(3-amino-4-imino-5-phenyl-3,4-dihydropyrido[2,3-d]pyrimidin-7-yl)phenyl]-2-phenyl-5-phenylhydrazono-3,5-dihydroimidazol-4-one

benzaldehyde

2-amino-6-{4-[5-oxo-2-phenyl-4-phenylhydrazono-4,5-dihydroimidazol-1-yl]phenyl}-4-phenylnicotinonitrile