C₂₂H₂₄ClN₃O₂

Base Information

• Chemical Name: C₂₂H₂₄ClN₃O₂
• CAS No.: 1027432-42-3
• Molecular Formula: C₂₂H₂₄ClN₃O₂
• Molecular Weight: 397.904
• Mol file: 1027432-42-3.mol

Synonyms:

Chemical Property of C₂₂H₂₄ClN₃O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₄ClN₃O₂

There total 6 articles about C₂₂H₂₄ClN₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3-chloro-2-methylphenyl)boronic acid (313545-20-9) → C22H24ClN3O2 (1027432-42-3)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine; copper diacetate / dichloromethane / 14 h / 20 °C / Molecular sieve

2: hydrazine / 1,4-dioxane / Reflux

With pyridine; copper diacetate; hydrazine; In 1,4-dioxane; dichloromethane;

DOI:10.1016/j.bmcl.2011.05.101

Reference yield:

C12H9ClFNO (1339959-08-8) → C22H24ClN3O2 (1027432-42-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine / 1,4-dioxane / Reflux

With hydrazine; In 1,4-dioxane;

DOI:10.1016/j.bmcl.2011.05.101

Reference yield:

2-fluoro-3-hydroxypyridine (174669-74-0) → C22H24ClN3O2 (1027432-42-3)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine; copper diacetate / dichloromethane / 14 h / 20 °C / Molecular sieve

2: hydrazine / 1,4-dioxane / Reflux

With pyridine; copper diacetate; hydrazine; In 1,4-dioxane; dichloromethane;

DOI:10.1016/j.bmcl.2011.05.101

upstream raw materials:

(3-chloro-2-methylphenyl)boronic acid

C₂₂H₂₆ClN₃O₃

C₁₂H₉ClFNO

C₁₂H₁₂ClN₃O

Downstream raw materials:

C₂₁H₂₃ClN₄O