4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(trifluoroacetate)

Base Information

• Chemical Name: 4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(trifluoroacetate)
• CAS No.: 1472611-44-1
• Molecular Formula: 3C₂HF₃O₂*C₃₁H₃₂N₈O₅
• Molecular Weight: 938.718

Synonyms:

Chemical Property of 4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(trifluoroacetate)

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Pyridostatin (trifluoroacetate salt) ≥95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Pyridostatin Trifluoroacetate Salt is G4s stabilizer.

Technology Process of 4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(trifluoroacetate)

There total 4 articles about 4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(trifluoroacetate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl-4-(2-(tert-butoxycarbonylamino)ethoxy)-2,6-pyridinedicarboxylate (1085412-34-5) → 4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(trifluoroacetate) (1472611-44-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: water; sodium hydroxide / methanol / 1 h / 20 °C

2.1: 1-chloro-1-(dimethylamino)-2-methyl-1-propene / dichloromethane / 2 h / 20 °C

2.2: 1 h / 0 - 20 °C

2.3: 20 °C / Inert atmosphere

3.1: dichloromethane / 1 h / 20 °C

With 1-chloro-1-(dimethylamino)-2-methyl-1-propene; water; sodium hydroxide; In methanol; dichloromethane;

DOI:10.1039/c2ob25830g

Reference yield:

2-amino-quinolin-4-ol (42712-64-1) → 4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(trifluoroacetate) (1472611-44-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 72 h / 0 - 20 °C / Inert atmosphere

2.1: 1-chloro-1-(dimethylamino)-2-methyl-1-propene / dichloromethane / 2 h / 20 °C

2.2: 1 h / 0 - 20 °C

2.3: 20 °C / Inert atmosphere

3.1: dichloromethane / 1 h / 20 °C

With 1-chloro-1-(dimethylamino)-2-methyl-1-propene; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; dichloromethane; 1.1: Mitsunobu reaction;

DOI:10.1039/c2ob25830g

Reference yield:

4-(2-tert-butoxycarbonylamino-ethoxy)-quinolin-2-yl amine (1085412-36-7) + 4-(2-(tert-butoxycarbonylamino)ethoxy)-2,6-pyridinedicarboxylic acid (1085412-35-6) → 4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(trifluoroacetate) (1472611-44-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 1-chloro-1-(dimethylamino)-2-methyl-1-propene / dichloromethane / 2 h / 20 °C

1.2: 1 h / 0 - 20 °C

1.3: 20 °C / Inert atmosphere

2.1: dichloromethane / 1 h / 20 °C

With 1-chloro-1-(dimethylamino)-2-methyl-1-propene; In dichloromethane;

DOI:10.1039/c2ob25830g

upstream raw materials:

4-(2-tert-butoxycarbonylamino-ethoxy)-quinolin-2-yl amine

4-(2-(tert-butoxycarbonylamino)ethoxy)-2,6-pyridinedicarboxylic acid

dimethyl-4-(2-(tert-butoxycarbonylamino)ethoxy)-2,6-pyridinedicarboxylate

2-amino-quinolin-4-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1472611-44-1 4-(2-aminoethoxy)-N2,N6-bis(4-(2-aminoethoxy)quinolin-2-yl)pyridine-2,6-dicarboxamide tris(trifluoroacetate)

Send

Send

Metric Ton KG G Pound L ML

Send

Send