2-Bromo-2-phenylacetamide

Base Information Edit

Chemical Name:2-Bromo-2-phenylacetamide
CAS No.:19078-71-8
Molecular Formula:C8H8 Br N O
Molecular Weight:214.062
Hs Code.:
NSC Number:50135
DSSTox Substance ID:DTXSID10287289
Nikkaji Number:J30.983D
ChEMBL ID:CHEMBL4744306
Mol file:19078-71-8.mol

Synonyms:2-bromo-2-phenylacetamide;19078-71-8;NSC 50135;NSC50135;Phenyl-brom-acetamid;alpha-bromophenylacetamide;2-Phenyl-2-bromoacetamide;SCHEMBL1320067;CHEMBL4744306;DTXSID10287289;NSC-50135

Suppliers and Price of 2-Bromo-2-phenylacetamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Bromo-2-phenylacetamide Edit

Chemical Property:

Vapor Pressure:0.000432mmHg at 25°C
Boiling Point:315.6°C at 760 mmHg
Flash Point:144.7°C
Density:1.562g/cm³
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:212.97893
Heavy Atom Count:11
Complexity:143

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C(=O)N)Br

Technology Process of 2-Bromo-2-phenylacetamide

There total 13 articles about 2-Bromo-2-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 103-81-1
Benzeneacetamide

: 19078-71-8
2-bromo-2-phenylethanamide

Guidance literature:: With N-Bromosuccinimide; In dichloromethane; at 18 - 25 ℃; for 24h; under UV light;

Reference yield:

: 19078-72-9
bromo(phenyl)acetyl chloride

: 19078-71-8
2-bromo-2-phenylethanamide

Guidance literature:: With ammonium hydroxide;
DOI:10.1021/ja01178a064

Reference yield:

: 4870-65-9,31302-84-8
2-bromophenylacetic acid

: 19078-71-8
2-bromo-2-phenylethanamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride; DMF / CH₂Cl₂ / 3 h

2: NH₃ gas / toluene; hexane / 1 h

With oxalyl dichloride; ammonia; N,N-dimethyl-formamide; In hexane; dichloromethane; toluene;
DOI:10.1021/jm020583i