Oxazole, 4-(3-nitrophenyl)-2-phenyl-

Base Information

Chemical Name:Oxazole, 4-(3-nitrophenyl)-2-phenyl-
CAS No.:119512-00-4
Molecular Formula:C15H10N2O3
Molecular Weight:266.256
Hs Code.:
DSSTox Substance ID:DTXSID70435002
Nikkaji Number:J2.330.246B

Synonyms:Oxazole, 4-(3-nitrophenyl)-2-phenyl-;119512-00-4;DTXSID70435002;2-Phenyl-4-(3-nitrophenyl)oxazole

Suppliers and Price of Oxazole, 4-(3-nitrophenyl)-2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of Oxazole, 4-(3-nitrophenyl)-2-phenyl-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:266.06914219
Heavy Atom Count:20
Complexity:339

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC(=CO2)C3=CC(=CC=C3)[N+](=O)[O-]

Technology Process of Oxazole, 4-(3-nitrophenyl)-2-phenyl-

There total 3 articles about Oxazole, 4-(3-nitrophenyl)-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 13331-27-6
m-nitrobenzene boronic acid

: 163936-42-3
trifluoromethanesulfonic acid 2-phenyl-oxazol-4-yl ester

: 119512-00-4
4-(3-nitrophenyl)-2-phenyloxazole

Guidance literature:: With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In 1,4-dioxane; at 150 ℃; for 0.333333h; microwave irradiation;
DOI:10.1021/ol060591j

Reference yield:

: 30216-01-4
2-phenyl-2-oxazolin-4-one

: 119512-00-4
4-(3-nitrophenyl)-2-phenyloxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / Et₃N / CH₂Cl₂ / 0.33 h / -78 - 20 °C

2: 92 percent / sodium carbonate / PdCl₂(PPh₃)2 / dioxane / 0.33 h / 150 °C / microwave irradiation

With sodium carbonate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In 1,4-dioxane; dichloromethane; 2: Suzuki coupling;
DOI:10.1021/ol060591j

Reference yield:

: 55-21-0,27208-38-4
benzamide

: 121-89-1
3-Nitroacetophenone

: 119512-00-4
4-(3-nitrophenyl)-2-phenyloxazole

Guidance literature:: With hydrogen bromide; pyridinium hydrobromide perbromide; Yield given. Multistep reaction; 1.) acetic acid, RT, 1 h, 2.) 150 deg C, 2 h;
DOI:10.1248/cpb.43.947