(+)-Methcathinone

Base Information

• Chemical Name: (+)-Methcathinone
• CAS No.: 160977-88-8
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.219

Synonyms:

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Chemical Property of (+)-Methcathinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-Methcathinone

There total 3 articles about (+)-Methcathinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,2R)-(+)-ephedrine (321-98-2,7009-81-6,90-83-5,6912-63-6) → (+)-Methcathinone (160977-88-8)

Guidance literature:

(1S,2R)-(+)-ephedrine; With sodium dichromate; sulfuric acid; In water; at 15 - 20 ℃; for 12.3333h;

With sodium hydroxide; In water; toluene; at 20 ℃; pH=10.5; Further stages;

DOI:10.1016/j.tetasy.2009.11.019

Reference yield:

2-(N-benzyl-N-methylamino)-1-phenylpropan-1-one (16735-30-1) → (+)-Methcathinone (160977-88-8)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium/charcoal; aqueous methanol. HCl / Hydrogenation

With hydrogenchloride; palladium on activated charcoal;

Reference yield:

methcathinone (5650-44-2,28521-94-0,112117-24-5) → (+)-Methcathinone (160977-88-8)

Guidance literature:

upstream raw materials:

methcathinone

2-(N-benzyl-N-methylamino)-1-phenylpropan-1-one

(1S,2R)-(+)-ephedrine

Downstream raw materials:

(1S,2R)-1-phenyl-1-methyl-2-methylamino-1-propanol hydrochloride