cyclopentyl phenylacetate

Base Information

• Chemical Name: cyclopentyl phenylacetate
• CAS No.: 5420-99-5
• Molecular Formula: C13H16 O2
• Molecular Weight: 204.269
• Mol file: 5420-99-5.mol

Synonyms:Cyclopentylphenylacetate; NSC 6625

Chemical Property of cyclopentyl phenylacetate

Chemical Property:

• Vapor Pressure: 0.00157mmHg at 25°C
• Boiling Point: 295°C at 760 mmHg
• Flash Point: 124.7°C
• Density: 1.07g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cyclopentyl phenylacetate

There total 3 articles about cyclopentyl phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

N,N,N--trimethyl--1--phenylmethanaminium trifluoromethanesulfonate (260783-80-0) + carbon monoxide (201230-82-2) + Cyclopentanol (96-41-3) → cyclopentyl 2-phenylacetate (5420-99-5)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; triphenylphosphine; In toluene; at 100 ℃; for 12h; under 760.051 Torr; Schlenk technique;

DOI:10.1039/c8ob00488a

Reference yield:

phenylacetic acid (103-82-2) + cyclopentyl methyl ether (5614-37-9) → 2-phenylethanol (60-12-8) + phenyl-acetic acid phenethyl ester (102-20-5) + cyclopentyl 2-phenylacetate (5420-99-5) + benzeneacetic acid methyl ester (101-41-7)

Guidance literature:

With aluminium(III) triflate; Co(acac)₃; hydrogen; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine]; at 140 ℃; for 18h; under 22502.3 Torr; Autoclave; Sealed tube;

DOI:10.1039/c7sc02117h

Reference yield:

N,N'-dimethylbenzylamine (103-83-3) → cyclopentyl 2-phenylacetate (5420-99-5)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / 0.5 h / 0 °C

2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triphenylphosphine; sodium carbonate / toluene / 12 h / 100 °C / 760.05 Torr / Schlenk technique

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; triphenylphosphine; In diethyl ether; toluene;

DOI:10.1039/c8ob00488a

upstream raw materials:

phenylacetic acid

cyclopentyl methyl ether

N,N'-dimethylbenzylamine

N,N,N--trimethyl--1--phenylmethanaminium trifluoromethanesulfonate

Downstream raw materials:

cyclopentene