N-(Naphthalen-2-yl)-2-hydroxyimino-acetamide

Base Information

• Chemical Name: N-(Naphthalen-2-yl)-2-hydroxyimino-acetamide
• CAS No.: 5580-64-3
• Molecular Formula: C12H10 N2 O2
• Molecular Weight: 214.224
• NSC Number: 16064
• Mol file: 5580-64-3.mol

Synonyms:NSC16064;ILGLRQPETIIUMV-MDWZMJQESA-N;5580-64-3;NSC-16064;N-(Naphthalen-2-yl)-2-hydroxyimino-acetamide;(2E)-2-(Hydroxyimino)-N-(2-naphthyl)ethanamide #

Chemical Property of N-(Naphthalen-2-yl)-2-hydroxyimino-acetamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 61.69000
• Density: 1.24g/cm³
• LogP: 2.31130
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 214.074227566
• Heavy Atom Count: 16
• Complexity: 278

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=C(C=CC2=C1)NC(=O)C=NO
• Isomeric SMILES: C1=CC=C2C=C(C=CC2=C1)NC(=O)/C=N/O

Technology Process of N-(Naphthalen-2-yl)-2-hydroxyimino-acetamide

There total 2 articles about N-(Naphthalen-2-yl)-2-hydroxyimino-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloral hydrate (302-17-0) + naphthalen-2-ylamine (91-59-8) → N-(α-Oximino-acetyl)-β-naphthylamin (5580-64-3)

Guidance literature:

With hydrogenchloride; hydroxylamine sulfate; sodium sulfate; In water;

DOI:10.1021/jm00105a034

Reference yield:

→ N-(α-Oximino-acetyl)-β-naphthylamin (5580-64-3)

Guidance literature:

2-Naphthylamin, Chloralhydrat, NH2OH*HCl;

Reference yield:

N-(α-Oximino-acetyl)-β-naphthylamin (5580-64-3) → 2-Amino-3-naphthoic acid (5959-52-4)

Guidance literature:

Multi-step reaction with 2 steps

1: CH₃SO₃H / 70 - 80 °C

2: KOH, KCl, 27percent H₂O₂ / 20 °C

With potassium hydroxide; methanesulfonic acid; potassium chloride; dihydrogen peroxide;

DOI:10.1021/jm00105a034

upstream raw materials:

chloral hydrate

naphthalen-2-ylamine

Downstream raw materials:

benzisatin

2-Amino-3-naphthoic acid