4-diphenylphosphinoyl-5-methylhex-2-enyl tert butyl(dimethyl)silyl ether

Base Information

• Chemical Name: 4-diphenylphosphinoyl-5-methylhex-2-enyl tert butyl(dimethyl)silyl ether
• CAS No.: 148314-49-2
• Molecular Formula: C₂₅H₃₇O₂PSi
• Molecular Weight: 428.627
• Mol file: 148314-49-2.mol

Synonyms:

Chemical Property of 4-diphenylphosphinoyl-5-methylhex-2-enyl tert butyl(dimethyl)silyl ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-diphenylphosphinoyl-5-methylhex-2-enyl tert butyl(dimethyl)silyl ether

There total 1 articles about 4-diphenylphosphinoyl-5-methylhex-2-enyl tert butyl(dimethyl)silyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) + (E)-4-diphenylphosphinoyl-5-methylhex-2-en-1-ol (145653-04-9) → 4-diphenylphosphinoyl-5-methylhex-2-enyl tert butyl(dimethyl)silyl ether (148314-49-2)

Guidance literature:

With 1H-imidazole;

DOI:10.1016/S0040-4039(00)91787-8

Reference yield:

4-diphenylphosphinoyl-5-methylhex-2-enyl tert butyl(dimethyl)silyl ether (148314-49-2) → (2RS,3SR,4RS)-4-diphenylphosphinoyl-2,3-epoxy-5-methylhexanyl (1,1-dimethylethyl)dimethylsilyl ether + (2RS,3SR,4SR)-4-diphenylphosphinoyl-2,3-epoxy-5-methylhexanyl (1,1-dimethylethyl)dimethylsilyl ether

Guidance literature:

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; for 96h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Ambient temperature;

Reference yield:

4-diphenylphosphinoyl-5-methylhex-2-enyl tert butyl(dimethyl)silyl ether (148314-49-2) → {(2S,3R)-3-[(R)-1-(Diphenyl-phosphinoyl)-2-methyl-propyl]-oxiranyl}-methanol + {(2R,3S)-3-[(R)-1-(Diphenyl-phosphinoyl)-2-methyl-propyl]-oxiranyl}-methanol

Guidance literature:

With disodium hydrogenphosphate; tetrabutyl ammonium fluoride; 3-chloro-benzenecarboperoxoic acid; Multistep reaction;

DOI:10.1016/S0040-4039(00)91787-8

upstream raw materials:

tert-butyldimethylsilyl chloride

(E)-4-diphenylphosphinoyl-5-methylhex-2-en-1-ol