C₂₄H₂₈FNO₆

Base Information

• Chemical Name: C₂₄H₂₈FNO₆
• CAS No.: 1042702-55-5
• Molecular Formula: C₂₄H₂₈FNO₆
• Molecular Weight: 445.488
• Mol file: 1042702-55-5.mol

Synonyms:

Chemical Property of C₂₄H₂₈FNO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₂₈FNO₆

There total 4 articles about C₂₄H₂₈FNO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[4-(benzyloxy)-2-fluorophenyl]-2-bromoethanone (850142-10-8) + N-(tert-butoxycarbonyl)-4-aminobutanoic acid (57294-38-9) → C24H28FNO6 (1042702-55-5)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃;

DOI:10.1139/V10-143

Reference yield:

3-fluorophenol (372-20-3) → C24H28FNO6 (1042702-55-5)

Guidance literature:

Multi-step reaction with 5 steps

1: bromine; trifluoroacetic acid / 20 °C

2: potassium carbonate / acetonitrile / 20 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / toluene / 100 °C

4: phenyltrimethylammonium tribromide / methanol; dichloromethane / 20 °C

5: potassium carbonate / acetonitrile / 20 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; bromine; phenyltrimethylammonium tribromide; potassium carbonate; trifluoroacetic acid; In methanol; dichloromethane; toluene; acetonitrile; 3: Stille coupling;

DOI:10.1139/V10-143

Reference yield:

2-fluoro-4-benzyloxyacetophenone (119776-15-7) → C24H28FNO6 (1042702-55-5)

Guidance literature:

Multi-step reaction with 2 steps

1: phenyltrimethylammonium tribromide / methanol; dichloromethane / 20 °C

2: potassium carbonate / acetonitrile / 20 °C

With phenyltrimethylammonium tribromide; potassium carbonate; In methanol; dichloromethane; acetonitrile;

DOI:10.1139/V10-143

upstream raw materials:

2-fluoro-4-benzyloxyacetophenone

1-[4-(benzyloxy)-2-fluorophenyl]-2-bromoethanone

N-(tert-butoxycarbonyl)-4-aminobutanoic acid

3-fluorophenol

Refernces