C₃₀H₃₂F₄O₃

Base Information

• Chemical Name: C₃₀H₃₂F₄O₃
• CAS No.: 221342-43-4
• Molecular Formula: C₃₀H₃₂F₄O₃
• Molecular Weight: 516.576
• Mol file: 221342-43-4.mol

Synonyms:

Chemical Property of C₃₀H₃₂F₄O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₃₂F₄O₃

There total 1 articles about C₃₀H₃₂F₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-(trimethylsilyloxy)-3-methyl-1-butene (17510-45-1) + spiro[3.5]non-7-en-6-one (221342-49-0) + 1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one (256424-38-1) → C30H32F4O3 (221342-43-4)

Guidance literature:

2-(trimethylsilyloxy)-3-methyl-1-butene; spiro[3.5]non-7-en-6-one; With titanium(IV) isopropylate; titanium tetrachloride; In dichloromethane;

1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one; In dichloromethane;

DOI:10.2533/000942904777678082

Reference yield:

C30H32F4O3 (221342-43-4) → C30H26F4O2 (221342-60-5)

Guidance literature:

C₃₀H₃₂F₄O₃; With pyridine; thionyl chloride;

With N-chloro-succinimide; dibenzoyl peroxide; In dichloromethane;

With air; 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,4-dioxane;

DOI:10.2533/000942904777678082

Reference yield:

C30H32F4O3 (221342-43-4) → BAY 38-1315

Guidance literature:

Multi-step reaction with 6 steps

1.1: SOCl₂; pyridine

1.2: NCS; (PhCO₂)2 / CH₂Cl₂

1.3: DBU; air / dioxane

2.1: BH₃*Et₂NPh; (1R,2S)-1-aminoindanol

3.1: dimethylformamide

4.1: LAH / tetrahydrofuran

5.1: DAST

6.1: TBAF

With pyridine; lithium aluminium tetrahydride; borane N,N-diethylaniline complex; thionyl chloride; (1R,2S)-1-Amino-2-indanol; tetrabutyl ammonium fluoride; 4,4'-diaminostilbene-2,2'-disulfonic acid; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.2533/000942904777678082

upstream raw materials:

2-(trimethylsilyloxy)-3-methyl-1-butene

spiro[3.5]non-7-en-6-one

1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one

Downstream raw materials:

C₃₀H₂₆F₄O₂

C₃₀H₂₈F₄O₂

C₃₆H₄₃F₅OSi

C₃₆H₄₂F₄O₂Si