16-Epivellosimine

Base Information

Chemical Name:16-Epivellosimine
CAS No.:88199-28-4
Molecular Formula:C₁₉H₂₀N₂O
Molecular Weight:292.381
Hs Code.:
DSSTox Substance ID:DTXSID401343059
Metabolomics Workbench ID:50493
Wikidata:Q27101896

Synonyms:16-Epivellosimine;16-episarpagan-17-al;CHEBI:16425;(16S,19E)-sarpagan-17-al;DTXSID401343059;88199-28-4;Q27101896;(1S,12S,13S,14R,15E)-15-ethylidene-3,17-diazapentacyclo[12.3.1.02,10.04,9.012,17]octadeca-2(10),4,6,8-tetraene-13-carbaldehyde

Suppliers and Price of 16-Epivellosimine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 16-Epivellosimine

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:292.157563266
Heavy Atom Count:22
Complexity:516

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC=C1CN2C3CC1C(C2CC4=C3NC5=CC=CC=C45)C=O
Isomeric SMILES:C/C=C\1/CN2[C@H]3C[C@@H]1[C@@H]([C@@H]2CC4=C3NC5=CC=CC=C45)C=O

Technology Process of 16-Epivellosimine

There total 23 articles about 16-Epivellosimine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: (3E,6S,9aS)-3-ethylidene-1-(methoxymethylene)hexahydro-1H-2,6-methanoquinolizin-7(2H)-one

: 100-63-0
phenylhydrazine

: 6874-98-2,88199-28-4,124096-80-6
(+)-vellosimine

Guidance literature:: (3E,6S,9aS)-3-ethylidene-1-(methoxymethylene)hexahydro-1H-2,6-methanoquinolizin-7(2H)-one; phenylhydrazine; In ethanol; for 6h; Inert atmosphere; Reflux;

With hydrogenchloride; acetyl chloride; In ethanol; for 2h; Inert atmosphere; Reflux;
DOI:10.1002/anie.201407280

Reference yield: 55.0%

: 2520-44-7,92218-35-4
(2S,6S,13S)-3-Eth-(E)-ylidene-13-formyl-1,3,4,7,12,12b-hexahydro-2H,6H-2,6-methano-indolo[2,3-a]quinolizine-13-carboxylic acid methyl ester

: 6874-98-2,88199-28-4,124096-80-6
vellosimine

Guidance literature:: With hydrogenchloride; potassium hydroxide; 1) 30 deg C, 6 hr, 2) water bath, 90 deg C, 10 min;

Reference yield:

: 6874-98-2,88199-28-4,124096-80-6
16-epi-vellosimine

: 34020-07-0
vinorine

: 6874-98-2,88199-28-4,124096-80-6
(+)-vellosimine

Guidance literature:: With enzyme extracted from R_. serpentina; acetylcoenzyme A; In various solvent(s); for 1.5h;
DOI:10.1016/S0040-4039(00)88395-1