(3,4-dimethoxy-phenyl)-succinic acid

Base Information

• Chemical Name: (3,4-dimethoxy-phenyl)-succinic acid
• CAS No.: 38175-27-8
• Molecular Formula: C₁₂H₁₄O₆
• Molecular Weight: 254.24
• Mol file: 38175-27-8.mol

Synonyms:

Chemical Property of (3,4-dimethoxy-phenyl)-succinic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3,4-dimethoxy-phenyl)-succinic acid

There total 6 articles about (3,4-dimethoxy-phenyl)-succinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

→ (3,4-dimethoxy-phenyl)-succinic acid (38175-27-8)

Guidance literature:

Reference yield:

3,4-dimethoxy-benzaldehyde (120-14-9) → (3,4-dimethoxy-phenyl)-succinic acid (38175-27-8)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine; acetic acid / toluene / Reflux

2: potassium cyanide / water; ethanol

With piperidine; potassium cyanide; acetic acid; In ethanol; water; toluene;

DOI:10.1039/c5ob00350d

Reference yield:

ethyl α-cyano-β-(3,4-dimethoxyphenyl)acrylate (2286-55-7) → (3,4-dimethoxy-phenyl)-succinic acid (38175-27-8)

Guidance literature:

ethyl α-cyano-β-(3,4-dimethoxyphenyl)acrylate; With potassium cyanide; In ethanol; water;

With hydrogenchloride; In water;

DOI:10.1039/c5ob00350d

upstream raw materials:

ethanol

ethyl (E)-2-cyano-3-(3,4-dimethoxyphenyl)-2-propenoate

potassium cyanide

3,4-dimethoxy-benzaldehyde

Downstream raw materials:

5,6-dimethoxyindan-1-carboxylic acid

(3S,7aR)-6-(3,4-Dimethoxy-phenyl)-3-phenyl-tetrahydro-pyrrolo[2,1-b]oxazol-5-one

Refernces

• 1、 -. "TETRAHYDRO ISOQUINOLINE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF". Page/Page column 9. . Retrieved 2009/04/23.