4-Methyl-N-(2,4,6-trimethylphenyl)benzene-1-carboximidoyl chloride

Base Information

• Chemical Name: 4-Methyl-N-(2,4,6-trimethylphenyl)benzene-1-carboximidoyl chloride
• CAS No.: 121408-20-6
• Molecular Formula: C₁₇H₁₈ClN
• Molecular Weight: 271.79
• DSSTox Substance ID: DTXSID20557223
• Nikkaji Number: J450.186A
• Mol file: 121408-20-6.mol

Synonyms:121408-20-6;DTXSID20557223;4-Methyl-N-(2,4,6-trimethylphenyl)benzene-1-carboximidoyl chloride

Chemical Property of 4-Methyl-N-(2,4,6-trimethylphenyl)benzene-1-carboximidoyl chloride

Chemical Property:

• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 271.1127773
• Heavy Atom Count: 19
• Complexity: 305

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(=NC2=C(C=C(C=C2C)C)C)Cl

Technology Process of 4-Methyl-N-(2,4,6-trimethylphenyl)benzene-1-carboximidoyl chloride

There total 1 articles about 4-Methyl-N-(2,4,6-trimethylphenyl)benzene-1-carboximidoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2,4,6-trimethylphenyl)-4-methylbenzamide (86489-65-8) → 4-Methyl-N-(2,4,6-trimethyl-phenyl)-benzimidoyl chloride (121408-20-6)

Guidance literature:

With thionyl chloride; In neat (no solvent); Reflux;

DOI:10.1039/c2dt31989f

Reference yield:

4-Methyl-N-(2,4,6-trimethyl-phenyl)-benzimidoyl chloride (121408-20-6) → C17H18N2O3 (121408-29-5)

Guidance literature:

With silver nitrate; In [D₃]acetonitrile; at 21.9 ℃; for 0.416667h;

Reference yield:

1-methyl-1H-imidazole (616-47-7) + 4-Methyl-N-(2,4,6-trimethyl-phenyl)-benzimidoyl chloride (121408-20-6) → C21H24N3(1+)*Cl(1-) + C21H24N3(1+)*Cl(1-)

Guidance literature:

In tetrahydrofuran; at 20 ℃; Overall yield = 80 %; Inert atmosphere;

DOI:10.1039/c2dt31989f

upstream raw materials:

N-(2,4,6-trimethylphenyl)-4-methylbenzamide

Downstream raw materials:

C₁₇H₁₈N₂O₃