Benzamide, N,N-diethyl-5-methoxy-2-(methylthio)-

Base Information

Chemical Name:Benzamide, N,N-diethyl-5-methoxy-2-(methylthio)-
CAS No.:121425-05-6
Molecular Formula:C13H19NO2S
Molecular Weight:253.365
Hs Code.:
DSSTox Substance ID:DTXSID20461674
Nikkaji Number:J1.920.532K
Wikidata:Q82286058
Mol file:121425-05-6.mol

Synonyms:Benzamide, N,N-diethyl-5-methoxy-2-(methylthio)-;121425-05-6;DTXSID20461674

Suppliers and Price of Benzamide, N,N-diethyl-5-methoxy-2-(methylthio)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzamide, N,N-diethyl-5-methoxy-2-(methylthio)-

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:253.11365002
Heavy Atom Count:17
Complexity:244

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)C(=O)C1=C(C=CC(=C1)OC)SC

Technology Process of Benzamide, N,N-diethyl-5-methoxy-2-(methylthio)-

There total 6 articles about Benzamide, N,N-diethyl-5-methoxy-2-(methylthio)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 121424-95-1
N,N-diethyl-3-methoxy-6-(methylthio)-2-(trimethylsilyl)benzamide

: 121425-05-6
N,N-diethyl-2-methylsulfanyl-53-methoxybenzamide

Guidance literature:: With cesium fluoride; In water; N,N-dimethyl-formamide; Heating;
DOI:10.1016/S0040-4020(03)00710-5

Reference yield: 83.0%

: sodium thiomethanolate

: 133730-33-3
N,N-Diethyl-2-bromo-5-methoxybenzamide

: 121425-05-6
N,N-diethyl-2-methylsulfanyl-53-methoxybenzamide

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 100 ℃; for 60h; Sealed tube;
DOI:10.1002/chem.201700826

Reference yield:

: 85370-85-0
N,N-diethyl-3-methoxy-2-(trimethylsilyl)benzamide

: 121425-05-6
N,N-diethyl-2-methylsulfanyl-53-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sec-BuLi; TMEDA / tetrahydrofuran; cyclohexane / 0.5 h / -78 °C

1.2: 79 percent / tetrahydrofuran; cyclohexane / -78 - 20 °C

2.1: 90 percent / CsF / dimethylformamide; H₂O / Heating

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; cesium fluoride; In tetrahydrofuran; cyclohexane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(03)00710-5