C₆₅H₈₇N₅O₁₂Si₃

Base Information

• Chemical Name: C₆₅H₈₇N₅O₁₂Si₃
• CAS No.: 500354-63-2
• Molecular Formula: C₆₅H₈₇N₅O₁₂Si₃
• Molecular Weight: 1214.69
• Mol file: 500354-63-2.mol

Synonyms:

Chemical Property of C₆₅H₈₇N₅O₁₂Si₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₅H₈₇N₅O₁₂Si₃

There total 12 articles about C₆₅H₈₇N₅O₁₂Si₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butylchlorodiphenylsilane (58479-61-1) → C65H87N5O12Si3 (500354-63-2)

Guidance literature:

Multi-step reaction with 9 steps

1: imidazole / dimethylformamide

2: H₂ / Pd-C / methanol

3: BOP; EtN(iPr)2 / dimethylformamide

4: trifluoroacetic acid / CHCl₃

5: PivCl; Et₃N; MS 4 Angstroem / dimethylformamide

6: LiOH / methanol

7: BOP; NEt(iPr)2 / dimethylformamide

8: trifluoroacetic acid / CHCl₃

9: imidazole / dimethylformamide

With 1H-imidazole; lithium hydroxide; MS 4 Angstroem; hydrogen; pivaloyl chloride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; palladium on activated charcoal; In methanol; chloroform; N,N-dimethyl-formamide;

DOI:10.1246/cl.2002.1098

Reference yield:

(S)-5,2',2'-Trimethyl-4',5'-dihydro-[2,4']bioxazolyl-4,3'-dicarboxylic acid 3'-benzyl ester 4-methyl ester (334832-21-2) → C65H87N5O12Si3 (500354-63-2)

Guidance literature:

Multi-step reaction with 10 steps

1: trifluoroacetic acid / CHCl₃

2: imidazole / dimethylformamide

3: H₂ / Pd-C / methanol

4: BOP; EtN(iPr)2 / dimethylformamide

5: trifluoroacetic acid / CHCl₃

6: PivCl; Et₃N; MS 4 Angstroem / dimethylformamide

7: LiOH / methanol

8: BOP; NEt(iPr)2 / dimethylformamide

9: trifluoroacetic acid / CHCl₃

10: imidazole / dimethylformamide

With 1H-imidazole; lithium hydroxide; MS 4 Angstroem; hydrogen; pivaloyl chloride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; palladium on activated charcoal; In methanol; chloroform; N,N-dimethyl-formamide;

DOI:10.1246/cl.2002.1098

Reference yield:

2-((S)-1-Benzyloxycarbonylamino-2-hydroxy-ethyl)-5-methyl-oxazole-4-carboxylic acid methyl ester → C65H87N5O12Si3 (500354-63-2)

Guidance literature:

Multi-step reaction with 9 steps

1: imidazole / dimethylformamide

2: H₂ / Pd-C / methanol

3: BOP; EtN(iPr)2 / dimethylformamide

4: trifluoroacetic acid / CHCl₃

5: PivCl; Et₃N; MS 4 Angstroem / dimethylformamide

6: LiOH / methanol

7: BOP; NEt(iPr)2 / dimethylformamide

8: trifluoroacetic acid / CHCl₃

9: imidazole / dimethylformamide

With 1H-imidazole; lithium hydroxide; MS 4 Angstroem; hydrogen; pivaloyl chloride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; palladium on activated charcoal; In methanol; chloroform; N,N-dimethyl-formamide;

DOI:10.1246/cl.2002.1098

upstream raw materials:

tert-butyldimethylsilyl chloride

N-(tert-butoxycarbonyl)-3-hydroxy-L-valine

tert-butylchlorodiphenylsilane

(S)-5,2',2'-Trimethyl-4',5'-dihydro-[2,4']bioxazolyl-4,3'-dicarboxylic acid 3'-benzyl ester 4-methyl ester