Technology Process of Z-Phe-Phe-Ala-OCAM
There total 7 articles about Z-Phe-Phe-Ala-OCAM which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Carbonate buffer;
In
N,N-dimethyl-formamide;
for 0.0833333h;
Ambient temperature;
α-chymotrypsin;
DOI:10.1007/BF00811332
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 58 percent / 1.) KOH / 1.) EtOH, H2O, 2.) DMF, 8 h, 60 deg C
2: 26 percent / carbonate buffer (pH=9) / dimethylformamide / 0.08 h / Ambient temperature; α-chymotrypsin
3: HBr, AcOH
4: 48 percent / carbonate buffer (pH=9) / dimethylformamide / 0.08 h / Ambient temperature; α-chymotrypsin
With
potassium hydroxide; Carbonate buffer; hydrogen bromide; acetic acid;
In
N,N-dimethyl-formamide;
DOI:10.1007/BF00811332
- Guidance literature:
-
Multi-step reaction with 5 steps
1: H2O / dimethylformamide / carbonate buffer, pH=10.5; α-chymotrypsin-cat. hydrolysis (spec. activity)
2: 58 percent / 1.) KOH / 1.) EtOH, H2O, 2.) DMF, 8 h, 60 deg C
3: 26 percent / carbonate buffer (pH=9) / dimethylformamide / 0.08 h / Ambient temperature; α-chymotrypsin
4: HBr, AcOH
5: 48 percent / carbonate buffer (pH=9) / dimethylformamide / 0.08 h / Ambient temperature; α-chymotrypsin
With
potassium hydroxide; Carbonate buffer; water; hydrogen bromide; acetic acid;
In
N,N-dimethyl-formamide;
DOI:10.1007/BF00811332
