1-(p-ethoxycarbonylphenyl)-1'-(4-ethoxycarbonyl-1-naphthyl)ferrocene

Base Information

• Chemical Name: 1-(p-ethoxycarbonylphenyl)-1'-(4-ethoxycarbonyl-1-naphthyl)ferrocene
• CAS No.: 100188-03-2
• Molecular Formula: C₃₂H₂₈FeO₄
• Molecular Weight: 532.419
• Mol file: 100188-03-2.mol

Synonyms:

Chemical Property of 1-(p-ethoxycarbonylphenyl)-1'-(4-ethoxycarbonyl-1-naphthyl)ferrocene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(p-ethoxycarbonylphenyl)-1'-(4-ethoxycarbonyl-1-naphthyl)ferrocene

There total 1 articles about 1-(p-ethoxycarbonylphenyl)-1'-(4-ethoxycarbonyl-1-naphthyl)ferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 15.3%

(p-ethoxycarbonylphenyl)ferrocene (58482-66-9) + 4-Ethoxycarbonyl-1-naphthylamine (95092-84-5) → 1-(p-ethoxycarbonylphenyl)-1'-(4-ethoxycarbonyl-1-naphthyl)ferrocene (100188-03-2)

Guidance literature:

With sulfuric acid; sodium nitrite; In water; acetic acid; amine diazotized in 5% H2SO4 at 0-5°C with NaNO2, added rapidly to soln. of CpFe(C5H4C6H4CO2Et) in CH3COOH under N2, stirred overnight at room temp., poured into H2O; extd. with CHCl3, washed with 5% aq. NaHCO3 and brine, dried over anhyd. MgSO4, filtered, concd., chromd. (SiO2, hexane-Et2O (4:1)); elem. anal.;

DOI:10.1246/bcsj.58.1560

Reference yield: 90.0%

lithium aluminium tetrahydride (16853-85-3) + 1-(p-ethoxycarbonylphenyl)-1'-(4-ethoxycarbonyl-1-naphthyl)ferrocene (100188-03-2) → 1-[p-(hydroxymethyl)phenyl]-1'-[4-(hydroxymethyl)-1-naphthyl]ferrocene (100203-44-9)

Guidance literature:

In diethyl ether; benzene; to suspn. of LiAlH4 in anhyd. Et2O added dropwise soln. of Fe complex in dry C6H6 at room temp. over 1 h, heated under reflux for 4 h, decompd.with cold water; org. layer washed succesively with 5% aq. HCl, 5% NaHCO3, and brine,dried over anhyd. MgSO4, evapd., chromd. (SiO2, C6H6-Et2O (1:1)), recrystd.from EtOH; elem. anal.;

DOI:10.1246/bcsj.58.1560

upstream raw materials:

(p-ethoxycarbonylphenyl)ferrocene

4-Ethoxycarbonyl-1-naphthylamine

Downstream raw materials:

1-[p-(hydroxymethyl)phenyl]-1'-[4-(hydroxymethyl)-1-naphthyl]ferrocene

Refernces