2-(4-methylphenyl)-2-(phenylamino)acetonitrile

Base Information

• Chemical Name: 2-(4-methylphenyl)-2-(phenylamino)acetonitrile
• CAS No.: 64101-91-3
• Molecular Formula: C₁₅H₁₄N₂
• Molecular Weight: 222.29
• Mol file: 64101-91-3.mol

Synonyms:

Chemical Property of 2-(4-methylphenyl)-2-(phenylamino)acetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-methylphenyl)-2-(phenylamino)acetonitrile

There total 19 articles about 2-(4-methylphenyl)-2-(phenylamino)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trimethylsilyl cyanide (7677-24-9) + (4-methylbenzylidene)phenylamine (2362-77-8) → 2-(4-methylphenyl)-2-(phenylamino)acetonitrile (64101-91-3,32323-81-2)

Guidance literature:

(4-methylbenzylidene)phenylamine; With magnesium iodide etherate; In dichloromethane; at 20 ℃; for 0.166667h;

trimethylsilyl cyanide; In dichloromethane; at 20 ℃; for 3h;

DOI:10.3184/174751913X13817705381783

Reference yield: 98.0%

trimethylsilyl cyanide (7677-24-9) + 4-methyl-benzaldehyde (104-87-0) + aniline (62-53-3) → 2-(4-methylphenyl)-2-(phenylamino)acetonitrile (64101-91-3,32323-81-2)

Guidance literature:

With titanium(IV) oxide; In acetonitrile; at 20 ℃; for 0.233333h;

DOI:10.1016/j.cclet.2010.12.003

Reference yield: 98.0%

sodium cyanide (773837-37-9) + 4-methyl-benzaldehyde (104-87-0) + aniline (62-53-3) → 2-(4-methylphenyl)-2-(phenylamino)acetonitrile (64101-91-3,32323-81-2)

Guidance literature:

With Cu(II)-imidazolium-containing Schiff base complex immobiized on SiO₂-coated Fe₃O₄ nanoparticles networked with melamine; In water; at 20 ℃; for 0.8h; Catalytic behavior;

DOI:10.1002/aoc.5388

upstream raw materials:

(4-methylbenzylidene)phenylamine

potassium cyanide

4-methyl-benzaldehyde

aniline

Downstream raw materials:

α-Cyano-p-methylbenzylidenanilin

Phenylamino-p-tolyl-acetic acid; hydrochloride

N-(2-amino-1-p-tolylethyl)benzenamine

(1-Phenyl-5-p-tolyl-4,5-dihydro-1H-imidazol-2-yl)-carbamic acid methyl ester