C₂₆H₁₈N₂O₃

Base Information

• Chemical Name: C₂₆H₁₈N₂O₃
• CAS No.: 1280681-97-1
• Molecular Formula: C₂₆H₁₈N₂O₃
• Molecular Weight: 406.441
• Mol file: 1280681-97-1.mol

Synonyms:

Chemical Property of C₂₆H₁₈N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₁₈N₂O₃

There total 3 articles about C₂₆H₁₈N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

N-methylmaleimide (930-88-1) + 3,4-diphenyl-2H-isoquinolin-1-one (93119-96-1) → C26H18N2O3 (1280681-97-1)

Guidance literature:

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; copper diacetate; In acetonitrile; at 115 ℃; for 16h; sealed tube; Inert atmosphere;

DOI:10.1021/jo2002209

Reference yield:

diphenyl acetylene (501-65-5) → C26H18N2O3 (1280681-97-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate / methanol / 60 °C

2: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; copper diacetate / acetonitrile / 16 h / 115 °C / sealed tube; Inert atmosphere

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; copper diacetate; In methanol; acetonitrile;

DOI:10.1021/jo2002209

Reference yield:

N-methoxybenzamide (2446-51-7) → C26H18N2O3 (1280681-97-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate / methanol / 60 °C

2: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; copper diacetate / acetonitrile / 16 h / 115 °C / sealed tube; Inert atmosphere

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; copper diacetate; In methanol; acetonitrile;

DOI:10.1021/jo2002209

upstream raw materials:

N-methylmaleimide

3,4-diphenyl-2H-isoquinolin-1-one

N-methoxybenzamide

diphenyl acetylene