Ethanol, 2-(methyl-2-pyrimidinylamino)-

Base Information

Chemical Name:Ethanol, 2-(methyl-2-pyrimidinylamino)-
CAS No.:122320-79-0
Molecular Formula:C7H11N3O
Molecular Weight:153.184
Hs Code.:
DSSTox Substance ID:DTXSID50439528
Wikidata:Q82255494
Mol file:122320-79-0.mol

Synonyms:122320-79-0;2-(Methyl(pyrimidin-2-yl)amino)ethanol;Ethanol, 2-(methyl-2-pyrimidinylamino)-;2-[N-methyl-N-(2-pyrimidinyl)amino]ethanol;SCHEMBL6158014;DTXSID50439528;UUTYBKYADBUNKX-UHFFFAOYSA-N;2-(methyl-2-pyrimidylamino)ethanol;AKOS008948477;AT18112;2-[N-Methyl-N-(2-pvrimidinyl)amino]ethanol;2-(METHYL(PYRIMIDIN-2-YL)AMINO)ETHAN-1-OL

Suppliers and Price of Ethanol, 2-(methyl-2-pyrimidinylamino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethanol, 2-(methyl-2-pyrimidinylamino)-

Chemical Property:

XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:153.090211983
Heavy Atom Count:11
Complexity:104

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(CCO)C1=NC=CC=N1

Technology Process of Ethanol, 2-(methyl-2-pyrimidinylamino)-

There total 1 articles about Ethanol, 2-(methyl-2-pyrimidinylamino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 109-83-1
(2-hydroxyethyl)(methyl)amine

: 1722-12-9,1195939-87-7
2-chloropyrimidine

: 122320-79-0
2-[N-methyl-N-(2-pyrimidinyl)amino]ethanol

: 122320-78-9
4-[2-(N-Methyl-N-(2-pyrimidinyl)amino)ethoxy]-benzaldehyde

Guidance literature:: In tetrahydrofuran; water;

Reference yield: 72.0%

: 459-57-4
4-fluorobenzaldehyde

: 122320-79-0
2-[N-methyl-N-(2-pyrimidinyl)amino]ethanol

: 122320-78-9
4-[2-(N-Methyl-N-(2-pyrimidinyl)amino)ethoxy]-benzaldehyde

Guidance literature:: With sodium chloride; In ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 122320-79-0
2-[N-methyl-N-(2-pyrimidinyl)amino]ethanol

: 5-(4-[2-(N-methyl-N-(2-pyrimidinyl)amino)ethoxy]benzyl)-2,4-thiazolidinedione

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) DMF, RT, 2.) DMF, RT, 18 h

2: piperidinium acetate / toluene / 2 h / Heating

3: 21 percent / H₂ / 10percent Pd/C / dioxane / 18 °C / 760 Torr

With hydrogen; piperdinium acetate; sodium hydride; palladium on activated charcoal; In 1,4-dioxane; toluene;
DOI:10.1021/jm00049a017