1-{4-[(Pyridin-2-yl)oxy]phenyl}ethan-1-one

Base Information

Chemical Name:1-{4-[(Pyridin-2-yl)oxy]phenyl}ethan-1-one
CAS No.:122399-89-7
Molecular Formula:C13H11NO2
Molecular Weight:213.236
Hs Code.:
DSSTox Substance ID:DTXSID60559827
Wikidata:Q82442678
Mol file:122399-89-7.mol

Synonyms:122399-89-7;1-{4-[(Pyridin-2-yl)oxy]phenyl}ethan-1-one;SCHEMBL5598667;DTXSID60559827;ABKAKPYZLKXZLH-UHFFFAOYSA-N;4'-(pyridine-2-yloxy)acetophenone;1-(4-(Pyridin-2-yloxy)phenyl)ethanone

Suppliers and Price of 1-{4-[(Pyridin-2-yl)oxy]phenyl}ethan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-{4-[(Pyridin-2-yl)oxy]phenyl}ethan-1-one

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:213.078978594
Heavy Atom Count:16
Complexity:234

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC=C(C=C1)OC2=CC=CC=N2

Technology Process of 1-{4-[(Pyridin-2-yl)oxy]phenyl}ethan-1-one

There total 5 articles about 1-{4-[(Pyridin-2-yl)oxy]phenyl}ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 4-acetylphenyl pyridine-2-sulfonate

: 122399-89-7
1-(4-(pyridin-2-yloxy)phenyl)ethan-1-one

Guidance literature:: With potassium phosphate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In toluene; at 160 ℃; for 16h; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.orglett.9b02858

Reference yield: 79.0%

: 372-48-5
2-fluoropyridine

: 99-93-4
4-Hydroxyacetophenone

: 122399-89-7
1-(4-(pyridin-2-yloxy)phenyl)ethan-1-one

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 100 ℃;

Reference yield: 48.0%

: 4-acetylphenyl picolinate

: 122399-89-7
1-(4-(pyridin-2-yloxy)phenyl)ethan-1-one

Guidance literature:: With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; potassium phosphate; 3,4-thiene-2,3-diylbis(dicyclohexylphosphine); In toluene; at 150 ℃; for 18h; Reagent/catalyst; Inert atmosphere; Glovebox; Sealed tube;
DOI:10.1021/jacs.7b00049