2,4-Diaminoquinazoline,5-benzyloxy

Base Information

Chemical Name:2,4-Diaminoquinazoline,5-benzyloxy
CAS No.:123241-95-2
Molecular Formula:C15H14N4O
Molecular Weight:266.302
Hs Code.:
ChEMBL ID:CHEMBL342595
DSSTox Substance ID:DTXSID00877739
Nikkaji Number:J272.204F
Wikidata:Q82859591
Mol file:123241-95-2.mol

Synonyms:CHEMBL342595;SCHEMBL1154438;DTXSID00877739;BDBM50237217;123241-95-2;2,4-DIAMINOQUINAZOLINE,5-BENZYLOXY

Suppliers and Price of 2,4-Diaminoquinazoline,5-benzyloxy

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2,4-Diaminoquinazoline,5-benzyloxy

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:266.11676108
Heavy Atom Count:20
Complexity:308

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC=CC3=C2C(=NC(=N3)N)N

Technology Process of 2,4-Diaminoquinazoline,5-benzyloxy

There total 8 articles about 2,4-Diaminoquinazoline,5-benzyloxy which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 94088-45-6
2-(benzyloxy)-6-fluorobenzonitrile

: 593-85-1,90332-86-8,3425-08-9
diguanidine carbonate

: 123241-95-2
5-(benzyloxy)quinazoline-2,4-diamine

Guidance literature:: In N,N-dimethyl acetamide; at 140 ℃;
DOI:10.1021/cb5009475

Reference yield: 29.0%

: 123241-46-3
2-amino-6-(benzyloxy)benzonitrile

: 29671-92-9
chloroformamidine hydrochloride

: 123241-95-2
5-(benzyloxy)quinazoline-2,4-diamine

Guidance literature:: In diethylene glycol dimethyl ether; at 130 - 140 ℃; for 3h;
DOI:10.1021/jm00163a067

Reference yield:

: 35213-00-4
2,6-dinitrobenzonitrile

: 123241-95-2
5-(benzyloxy)quinazoline-2,4-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: 53 percent / phenylmethanol; dimethylformamide / 2 h / Ambient temperature

2: 74 percent / tin(II) chloride hydrate, concentrated hydrochloric acid / bis-(2-methoxy-ethyl) ether / 1.5 h / Ambient temperature

3: 29 percent / bis-(2-methoxy-ethyl) ether / 3 h / 130 - 140 °C

With hydrogenchloride; tin(ll) chloride; In diethylene glycol dimethyl ether; N,N-dimethyl-formamide; benzyl alcohol;
DOI:10.1021/jm00163a067