Technology Process of 4-Ethoxycarbonylamino-2,3-dihydroxy-benzoic acid methyl ester
There total 7 articles about 4-Ethoxycarbonylamino-2,3-dihydroxy-benzoic acid methyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dmap; triethylamine;
In
N,N-dimethyl-formamide; toluene;
for 2h;
DOI:10.1002/jhet.5570330428
- Guidance literature:
-
Multi-step reaction with 6 steps
1: fuming nitric acid, conc. sulfuric acid / 0.08 h / -40 °C
2: 40 percent / potassium permanganate / acetone; H2O / 17 h / Ambient temperature
3: 93 percent / 47percent aq. HBr / acetic acid / 4 h / Heating
4: 51 percent / hexane; CHCl3; methanol / 1 h / Ambient temperature
5: 100 percent / 30percent HCl, H2 / 10percent Pd/C / methanol; H2O; ethanol / 1 h / Ambient temperature
6: 34 percent / triethylamine, 4-dimethylaminopyridine / toluene; dimethylformamide / 2 h
With
hydrogenchloride; dmap; potassium permanganate; sulfuric acid; hydrogen bromide; hydrogen; nitric acid; triethylamine;
palladium on activated charcoal;
In
methanol; ethanol; hexane; chloroform; water; acetic acid; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1002/jhet.5570330428
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 40 percent / potassium permanganate / acetone; H2O / 17 h / Ambient temperature
2: 93 percent / 47percent aq. HBr / acetic acid / 4 h / Heating
3: 51 percent / hexane; CHCl3; methanol / 1 h / Ambient temperature
4: 100 percent / 30percent HCl, H2 / 10percent Pd/C / methanol; H2O; ethanol / 1 h / Ambient temperature
5: 34 percent / triethylamine, 4-dimethylaminopyridine / toluene; dimethylformamide / 2 h
With
hydrogenchloride; dmap; potassium permanganate; hydrogen bromide; hydrogen; triethylamine;
palladium on activated charcoal;
In
methanol; ethanol; hexane; chloroform; water; acetic acid; N,N-dimethyl-formamide; acetone; toluene;
DOI:10.1002/jhet.5570330428
