2-Amino-alpha,alpha-bis(4-methoxyphenyl)benzenemethanol

Base Information

• Chemical Name: 2-Amino-alpha,alpha-bis(4-methoxyphenyl)benzenemethanol
• CAS No.: 91148-62-8
• Molecular Formula: C₂₁H₂₁NO₃
• Molecular Weight: 335.403
• DSSTox Substance ID: DTXSID501242836

Synonyms:2-Amino-alpha,alpha-bis(4-methoxyphenyl)benzenemethanol;DTXSID501242836;91148-62-8

Chemical Property of 2-Amino-alpha,alpha-bis(4-methoxyphenyl)benzenemethanol

Chemical Property:

• XLogP3: 4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 335.15214353
• Heavy Atom Count: 25
• Complexity: 376

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3N)O

Technology Process of 2-Amino-alpha,alpha-bis(4-methoxyphenyl)benzenemethanol

There total 3 articles about 2-Amino-alpha,alpha-bis(4-methoxyphenyl)benzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-4'-methoxybenzophenone (36192-61-7) + (4-methoxyphenyl)magnesium iodide (112219-63-3) → (2-Amino-phenyl)-bis-(4-methoxy-phenyl)-methanol (91148-62-8)

Guidance literature:

With diethyl ether;

Reference yield:

(4-methoxyphenyl)magnesium iodide (112219-63-3) + 2-carbomethoxyaniline (134-20-3) → (2-Amino-phenyl)-bis-(4-methoxy-phenyl)-methanol (91148-62-8)

Guidance literature:

With diethyl ether;

Reference yield:

→ (2-Amino-phenyl)-bis-(4-methoxy-phenyl)-methanol (91148-62-8)

Guidance literature:

Methylanthranilat, 4-Methoxy-phenyl-magnesium-bromid;

DOI:10.1021/jo01068a005

upstream raw materials:

2-amino-4'-methoxybenzophenone

(4-methoxyphenyl)magnesium iodide

2-carbomethoxyaniline

Downstream raw materials:

acetic acid-[2-(4,4'-dimethoxy-benzhydryl)-anilide]

4,4'-(2-amino-benzylidene)-di-phenol

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