<2-(2-Fluorophenyl)-1H-indol-3-yl>phenylethanone

Base Information

Chemical Name:<2-(2-Fluorophenyl)-1H-indol-3-yl>phenylethanone
CAS No.:94123-59-8
Molecular Formula:C₂₁H₁₄FNO
Molecular Weight:315.347
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of <2-(2-Fluorophenyl)-1H-indol-3-yl>phenylethanone

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Technology Process of <2-(2-Fluorophenyl)-1H-indol-3-yl>phenylethanone

There total 3 articles about <2-(2-Fluorophenyl)-1H-indol-3-yl>phenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 52765-22-7
2-(2-Fluorophenyl)-1H-indole

: 93-97-0
benzoic acid anhydride

: 94123-59-8
<2-(2-Fluorophenyl)-1H-indol-3-yl>phenylethanone

Guidance literature:: With boron trifluoride diethyl etherate; In chloroform; for 5.5h; Heating;
DOI:10.1002/jhet.5570210502

Reference yield:

: 445-27-2
2'-Fluoroacetophenone

: 94123-59-8
<2-(2-Fluorophenyl)-1H-indol-3-yl>phenylethanone

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / glacial acetic acid / aq. ethanol / 2 h / Ambient temperature

2: 67.5 percent / polyphosphoric acid / 0.58 h / 75 - 100 °C

3: 64 percent / boron trifluoride etherate / CHCl₃ / 5.5 h / Heating

With PPA; boron trifluoride diethyl etherate; acetic acid; In ethanol; chloroform;
DOI:10.1002/jhet.5570210502

Reference yield:

: 94123-57-6
1-(2-Fluorophenyl)ethanone phenylhydrazone

: 94123-59-8
<2-(2-Fluorophenyl)-1H-indol-3-yl>phenylethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 67.5 percent / polyphosphoric acid / 0.58 h / 75 - 100 °C

2: 64 percent / boron trifluoride etherate / CHCl₃ / 5.5 h / Heating

With PPA; boron trifluoride diethyl etherate; In chloroform;
DOI:10.1002/jhet.5570210502