(R)-((2R,4S)-4-{N'-[(2R,4S)-2-((R)-Methoxycarbonyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carbonyl]-hydrazinocarbonyl}-5,5-dimethyl-thiazolidin-2-yl)-phenylacetylamino-acetic acid methyl ester

Base Information

Chemical Name:(R)-((2R,4S)-4-{N'-[(2R,4S)-2-((R)-Methoxycarbonyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carbonyl]-hydrazinocarbonyl}-5,5-dimethyl-thiazolidin-2-yl)-phenylacetylamino-acetic acid methyl ester
CAS No.:142762-75-2
Molecular Formula:C₃₄H₄₄N₆O₈S₂
Molecular Weight:728.891
Hs Code.:

(R)-((2R,4S)-4-{N'-[(2R,4S)-2-((R)-Methoxycarbonyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carbonyl]-hydrazinocarbonyl}-5,5-dimethyl-thiazolidin-2-yl)-phenylacetylamino-acetic acid methyl ester

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Chemical Property of (R)-((2R,4S)-4-{N'-[(2R,4S)-2-((R)-Methoxycarbonyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carbonyl]-hydrazinocarbonyl}-5,5-dimethyl-thiazolidin-2-yl)-phenylacetylamino-acetic acid methyl ester

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Technology Process of (R)-((2R,4S)-4-{N'-[(2R,4S)-2-((R)-Methoxycarbonyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carbonyl]-hydrazinocarbonyl}-5,5-dimethyl-thiazolidin-2-yl)-phenylacetylamino-acetic acid methyl ester

There total 3 articles about (R)-((2R,4S)-4-{N'-[(2R,4S)-2-((R)-Methoxycarbonyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carbonyl]-hydrazinocarbonyl}-5,5-dimethyl-thiazolidin-2-yl)-phenylacetylamino-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 39879-63-5
penicillin-G N-ethylpiperidine salt

: 142762-75-2
(R)-((2R,4S)-4-{N'-[(2R,4S)-2-((R)-Methoxycarbonyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carbonyl]-hydrazinocarbonyl}-5,5-dimethyl-thiazolidin-2-yl)-phenylacetylamino-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 2 h / -10 °C

2: H₂NNH₂ / 2 h / 0 - 20 °C

3: Ambient temperature

With hydrazine; In dichloromethane;
DOI:10.1021/jm00094a024

Reference yield:

: 19870-47-4
benzylpenicillin-(carbonic acid ethyl ester)-anhydride

: 142762-75-2
(R)-((2R,4S)-4-{N'-[(2R,4S)-2-((R)-Methoxycarbonyl-phenylacetylamino-methyl)-5,5-dimethyl-thiazolidine-4-carbonyl]-hydrazinocarbonyl}-5,5-dimethyl-thiazolidin-2-yl)-phenylacetylamino-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂NNH₂ / 2 h / 0 - 20 °C

2: Ambient temperature

With hydrazine;
DOI:10.1021/jm00094a024