3-(DIMETHYLAMINO)AZETIDINE DIHYDROCHLORIDE

Base Information

• Chemical Name: 3-(DIMETHYLAMINO)AZETIDINE DIHYDROCHLORIDE
• CAS No.: 124668-49-1
• Molecular Formula: C5H12N2.2ClH
• Molecular Weight: 173.08400
• Hs Code.: 2933990090
• Mol file: 124668-49-1.mol

Synonyms:N,N-dimethylazetidin-3-amine,dihydrochloride;N,N-Dimethylazetidin-3-amine dihydrochloride;

Chemical Property of 3-(DIMETHYLAMINO)AZETIDINE DIHYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 6.701mmHg at 25°C
• Boiling Point: 138.528oC at 760 mmHg
• Flash Point: 47.914oC
• PSA: 15.27000
• Density: 0.933g/cm3
• LogP: 1.45260
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-(Dimethylamino)azetidinediHCl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(DIMETHYLAMINO)AZETIDINE DIHYDROCHLORIDE

There total 7 articles about 3-(DIMETHYLAMINO)AZETIDINE DIHYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-(dimethylamino)-1-(diphenylmethyl)azetidine (55438-79-4) → 3-(dimethylamino)azetidine dihydrochloride (124668-49-1)

Guidance literature:

3-(dimethylamino)-1-(diphenylmethyl)azetidine; With hydrogen; palladium(II) hydroxide/carbon; In ethanol; for 18h;

With hydrogenchloride; In ethanol;

Reference yield: 82.0%

tert-butyl 3-(dimethylamino)azetidine-1-carboxylate (792970-55-9) → 3-(dimethylamino)azetidine dihydrochloride (124668-49-1)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 3h;

Reference yield:

tert-butyl 3-(dimethylamino)azetidine-1-carboxylate (792970-55-9) → N,N-dimethylazetidin-3-amine monohydrochloride (935670-07-8,124668-49-1)

Guidance literature:

With hydrogenchloride; In diethyl ether; at 20 ℃; for 0.666667h;

upstream raw materials:

3-(dimethylamino)-1-(diphenylmethyl)azetidine

tert-butyl 3-(dimethylamino)azetidine-1-carboxylate

tert-butyl 3-oxoazetidine-1-carboxylate

dimethyl amine

Downstream raw materials:

5-chloro-N-[4-(3-dimethylaminoazetidin-1-yl)-2-methoxy-5-nitrophenyl]-4-pyrazolo[1,5-a]pyridin-3-ylpyrimidin-2-amine

N-[4-(3-dimethylaminoazetidin-1-yl)-2-methoxy-5-nitrophenyl]-4-(4,5,6,7-tetrahydropyrazolo[1,5-a]pyridin-3-yl)pyrimidin-2-amine

N-(2-methoxy-4-(3-(dimethylamino)cycloazan-1-yl)-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidine-2-amine

5-chloro-N-[4-(3-dimethylaminoazetidin-1-yl)-2-methoxy-5-nitrophenyl]-4-(1-methylindol-3-yl)pyrimidin-2-amine