2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl ester

Base Information

• Chemical Name: 2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl ester
• CAS No.: 135716-21-1
• Molecular Formula: C₂₇H₅₀O₅
• Molecular Weight: 454.691

Synonyms:

Chemical Property of 2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl ester

There total 8 articles about 2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[(1S,2S,3S,6S)-6-Allyl-2-(2-{(4R,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-3-methyl-cyclohexyl]-methanol (135716-19-7) → 2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl ester (135716-21-1)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / 10percent Pd-C / methanol

2: DMAP / pyridine

3: n-Bu₄NF / tetrahydrofuran

With dmap; tetrabutyl ammonium fluoride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; pyridine; methanol;

DOI:10.1016/0040-4039(91)80587-V

Reference yield:

(4aS,7S,8S,8aS)-8-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-7-methyl-octahydro-isochromen-3-ol (136491-76-4) → 2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl ester (135716-21-1)

Guidance literature:

Multi-step reaction with 4 steps

1: KHMDS / toluene

2: H₂ / 10percent Pd-C / methanol

3: DMAP / pyridine

4: n-Bu₄NF / tetrahydrofuran

With dmap; tetrabutyl ammonium fluoride; hydrogen; potassium hexamethylsilazane; palladium on activated charcoal; In tetrahydrofuran; pyridine; methanol; toluene;

DOI:10.1016/0040-4039(91)80587-V

Reference yield:

(4aS,7S,8S,8aS)-8-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-7-methyl-octahydro-isochromen-3-one (135734-44-0) → 2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl ester (135716-21-1)

Guidance literature:

Multi-step reaction with 5 steps

1: DiBAL / toluene / -78 °C

2: KHMDS / toluene

3: H₂ / 10percent Pd-C / methanol

4: DMAP / pyridine

5: n-Bu₄NF / tetrahydrofuran

With dmap; tetrabutyl ammonium fluoride; hydrogen; potassium hexamethylsilazane; diisobutylaluminium hydride; palladium on activated charcoal; In tetrahydrofuran; pyridine; methanol; toluene;

DOI:10.1016/0040-4039(91)80587-V

upstream raw materials:

2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-(2-{(4R,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-3-methyl-6-propyl-cyclohexylmethyl ester

2,2-dimethylbutanoyl chloride

[(1S,2S,3S,6R)-2-(2-{(4R,6S)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-3-methyl-6-propyl-cyclohexyl]-methanol

[(1S,2S,3S,6S)-6-Allyl-2-(2-{(4R,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-ethyl)-3-methyl-cyclohexyl]-methanol

Downstream raw materials:

2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-[2-((4R,6R)-6-carboxymethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-3-methyl-6-propyl-cyclohexylmethyl ester

[1S-[1α(βS*,δS*),2β,3α,6α]]-2-[(2,2-Dimethyl-1-oxobutoxy) methyl]-β,δ-dihydroxy-6-methyl-3-propylcyclohexaneheptanoic acid, monolithium salt

2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-[2-((4R,6R)-6-methoxycarbonylmethyl-2,2-dimethyl-[1,3]dioxan-4-yl)-ethyl]-3-methyl-6-propyl-cyclohexylmethyl ester

2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3-methyl-6-propyl-cyclohexylmethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 135716-21-1 2,2-Dimethyl-butyric acid (1S,2S,3S,6R)-2-{2-[(4R,6S)-6-(2-hydroxy-ethyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-ethyl}-3-methyl-6-propyl-cyclohexylmethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send