Technology Process of 15-(phenylethynyl)-3,7,11-tris(carboxymethyl)-3,7,11,17-tetraazabicyclo<11.3.1>heptadeca-1(17),13,15-triene
There total 10 articles about 15-(phenylethynyl)-3,7,11-tris(carboxymethyl)-3,7,11,17-tetraazabicyclo<11.3.1>heptadeca-1(17),13,15-triene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
for 1.5h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 4 steps
2: 39 percent / potassium carbonate / acetonitrile / 24 h / Ambient temperature
3: 63 percent / triethylamine / bis(triphenylphosphine)palladium(II) chloride, copper(I) iodide / tetrahydrofuran / 24 h / 45 °C
4: 100 percent / trifluoroacetic acid / 1.5 h / Ambient temperature
With
potassium carbonate; triethylamine; trifluoroacetic acid;
copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride;
In
tetrahydrofuran; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 4 steps
2: 39 percent / potassium carbonate / acetonitrile / 24 h / Ambient temperature
3: 63 percent / triethylamine / bis(triphenylphosphine)palladium(II) chloride, copper(I) iodide / tetrahydrofuran / 24 h / 45 °C
4: 100 percent / trifluoroacetic acid / 1.5 h / Ambient temperature
With
potassium carbonate; triethylamine; trifluoroacetic acid;
copper(l) iodide; bis(triphenylphosphine)palladium(II)-chloride;
In
tetrahydrofuran; acetonitrile;
![(7,11-Bis-tert-butoxycarbonylmethyl-15-phenylethynyl-3,7,11,17-tetraaza-bicyclo[11.3.1]heptadeca-1<sup>(16)</sup>,13<sup>(17)</sup>,14-trien-3-yl)-acetic acid tert-butyl ester](/Databaselist/images/loading.webp)
