4-(Tetrahydro-2h-pyran-4-yl)pyridine

Base Information

Chemical Name:4-(Tetrahydro-2h-pyran-4-yl)pyridine
CAS No.:26684-56-0
Molecular Formula:C₁₀H₁₃NO
Molecular Weight:163.219
Hs Code.:
European Community (EC) Number:653-752-2
NSC Number:158423
DSSTox Substance ID:DTXSID80303465
Wikidata:Q82048780

Synonyms:4-(tetrahydro-2h-pyran-4-yl)pyridine;26684-56-0;4-(Tetrahydropyran-4-yl)-pyridine;4-(oxan-4-yl)pyridine;NSC158423;SCHEMBL8126033;DTXSID80303465;AKOS024323765;NSC-158423;CS-0336114;A911054

Suppliers and Price of 4-(Tetrahydro-2h-pyran-4-yl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(Tetrahydro-2h-pyran-4-yl)pyridine

Chemical Property:

Vapor Pressure:0.012mmHg at 25°C
Boiling Point:269.4°C at 760 mmHg
Flash Point:98.7°C
Density:1.053g/cm³
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:163.099714038
Heavy Atom Count:12
Complexity:126

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCC1C2=CC=NC=C2

Technology Process of 4-(Tetrahydro-2h-pyran-4-yl)pyridine

There total 10 articles about 4-(Tetrahydro-2h-pyran-4-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 25637-16-5
4-bromotetrahydro-2H-pyran

: 19524-06-2
4-bromopyridine hydrochloride

: 26684-56-0
4-(tetrahydro-2H-pyran-4-yl)pyridine

Guidance literature:: With [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine]nickel(II) dichloride; tris-(trimethylsilyl)silane; [Ir[2-(2,4-difluorophenyl)-5-trifluoromethylpyridine]₂(4,4′-di-t-Bu-2,2′-bipyridine)]PF₆; lithium hydroxide; In 1,2-dimethoxyethane; at 20 ℃; for 6h; Inert atmosphere; Irradiation;
DOI:10.1021/jacs.6b04818

Reference yield: 66.0%

: diethyl 2,6-dimethyl-4-(tetrahydro-2H-pyran-4-yl)-1,4-dihydropyridine-3,5-dicarboxylate

: 1-((N,4-dimethylphenyl)sulfonamido)pyridin-1-ium tetrafluoroborate

: 26684-56-0
4-(tetrahydro-2H-pyran-4-yl)pyridine

Guidance literature:: In 1,2-dichloro-ethane; at 20 ℃; regioselective reaction; Inert atmosphere; Sealed tube; Irradiation;
DOI:10.1021/acs.orglett.0c03347

Reference yield: 58.0%

: 25637-16-5
4-bromotetrahydro-2H-pyran

: 1120-87-2
4-bromopyridin

: 26684-56-0
4-(tetrahydro-2H-pyran-4-yl)pyridine

Guidance literature:: With bis(1,3-bis((4-methyl-2-pyridyl)imino)isoindolinato)nickel(II); C₂₂H₁₉N₅NiO₂; sodium iodide; In N,N-dimethyl acetamide; at 20 ℃; Inert atmosphere; Electrolysis; Sealed tube;
DOI:10.1021/jacs.0c01475