1-[Dimethyl(phenyl)silyl]hexan-1-OL

Base Information

Chemical Name:1-[Dimethyl(phenyl)silyl]hexan-1-OL
CAS No.:125950-71-2
Molecular Formula:C14H24OSi
Molecular Weight:236.429
Hs Code.:
DSSTox Substance ID:DTXSID40562718
Nikkaji Number:J1.641.088H
Mol file:125950-71-2.mol

Synonyms:1-[DIMETHYL(PHENYL)SILYL]HEXAN-1-OL;125950-71-2;DTXSID40562718

Suppliers and Price of 1-[Dimethyl(phenyl)silyl]hexan-1-OL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-[Dimethyl(phenyl)silyl]hexan-1-OL

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:6
Exact Mass:236.159641919
Heavy Atom Count:16
Complexity:185

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC(O)[Si](C)(C)C1=CC=CC=C1

Technology Process of 1-[Dimethyl(phenyl)silyl]hexan-1-OL

There total 3 articles about 1-[Dimethyl(phenyl)silyl]hexan-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 3839-31-4
dimethyl(phenyl)silyllithium

: 66-25-1
hexanal

: 125950-71-2
dimethylphenyl(α-hydroxyhexyl)silane

Guidance literature:: In tetrahydrofuran; -78 to 0 deg C;
DOI:10.1016/S0040-4039(00)92687-X

Reference yield: 44.0%

: 66-25-1
hexanal

: 768-33-2
phenyldimethylsilyl chloride

: 125950-71-2
dimethylphenyl(α-hydroxyhexyl)silane

Guidance literature:: phenyldimethylsilyl chloride; With lithium; In tetrahydrofuran; at 20 ℃; for 31h;

hexanal; In tetrahydrofuran; at -78 ℃; for 0.5h;
DOI:10.1016/j.tetasy.2010.02.030

Reference yield:

: 125950-70-1
α-((dimethylphenylsilyl)oxy)hexyltributylstannane

: 125950-71-2
dimethylphenyl(α-hydroxyhexyl)silane

Guidance literature:: With n-butyllithium; In tetrahydrofuran; byproducts: Sn(Bu)4; dropwise addn. of n-BuLi in hexane to stannyl silyl ether in dry THF (under Ar, -78°C, via syringe), stirring (-78°C, 15 min), quenching at -78°C by rapid addn. of water; warming to room temp., extn. using petroleum ether, flash chromy. on silica gel, eluation of tetraalkylstannane (hexane), eluation of product (ethyl acetate/hexane);
DOI:10.1021/ja00162a048