Dalfopristin+Quinupristin

Base Information

Chemical Name:Dalfopristin+Quinupristin
CAS No.:126202-89-9
Molecular Formula:C₁₈H₁₂ClN₃
Molecular Weight:305.766
Hs Code.:
Mol file:126202-89-9.mol

Synonyms:

Suppliers and Price of Dalfopristin+Quinupristin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Dalfopristin+Quinupristin

Chemical Property:

Melting Point:226 °C
Boiling Point:527.3±50.0 °C(Predicted)
PKA:2.40±0.18(Predicted)
PSA：63.43000
Density:1.34±0.1 g/cm3(Predicted)
LogP:4.45298

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Clinical Use A drug combination of the streptogramins, quinupristin and dalfopristin was approved for IV use in the treatment of infections caused by vancomycin-resistant Enterococcus faeci um bacteremia as well as skin/skin structure infections caused by MRSA and methicillin-sensitive Streptococcus pyogenes. Certain strains of E. faecium are resistant to essentially all other antibiotics, including vancomycin. The streptogramin type A compound dalfopristin binds to the 50S ribosomal subparticle, resulting in a conformational change in the substrate. It appears that dalfopristin binding creates a high-affinity binding site for quinupristin, accounting for the synergy.

Technology Process of Dalfopristin+Quinupristin

There total 1 articles about Dalfopristin+Quinupristin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%