Technology Process of C19H15Cl2NO3
There total 2 articles about C19H15Cl2NO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: ethanol / 15 h / 20 °C
2.1: sodium ethanolate / ethanol / 1 h / Reflux
2.2: 4 h / Reflux
With
sodium ethanolate;
In
ethanol;
DOI:10.1016/j.bmcl.2011.09.074
- Guidance literature:
-
ethyl 3-[(4-methoxybenzyl)amino]propanoate; oxalic acid diethyl ester;
With
sodium ethanolate;
In
ethanol;
for 1h;
Reflux;
2,4-dichlorobenzaldeyhde;
With
hydrogenchloride;
In
ethanol; water;
for 4h;
Reflux;
DOI:10.1016/j.bmcl.2011.09.074
- Guidance literature:
-
Multi-step reaction with 8 steps
1: acetic acid / 1.5 h / Reflux
2: nitric acid / 0.5 h / Reflux
3: methanol; lithium borohydride / 15 h / 20 °C
4: methanesulfonyl chloride; triethylamine / dichloromethane / 2 h / 20 °C
5: ammonia / methanol / 0.08 h / 100 °C / Microwave condition
6: sodium hydrogencarbonate / tetrahydrofuran; water / 12 h / 20 °C
7: ammonium cerium (IV) nitrate / water; acetonitrile / 20 °C
8: pyridine; copper diacetate; triethylamine / 1,1-Dichloroethylene / 75 °C
With
pyridine; methanol; lithium borohydride; ammonium cerium (IV) nitrate; ammonia; nitric acid; copper diacetate; sodium hydrogencarbonate; acetic acid; methanesulfonyl chloride; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; 1,1-Dichloroethylene; water; acetonitrile;
DOI:10.1016/j.bmcl.2011.09.074
