(Z)-4-bromostyryl acetate

Base Information

• Chemical Name: (Z)-4-bromostyryl acetate
• CAS No.: 1527491-72-0
• Molecular Formula: C₁₀H₉BrO₂
• Molecular Weight: 241.084
• Mol file: 1527491-72-0.mol

Synonyms:

Chemical Property of (Z)-4-bromostyryl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-4-bromostyryl acetate

There total 3 articles about (Z)-4-bromostyryl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-bromophenylacetaldehyde (27200-79-9) + acetyl chloride (75-36-5) → (E)-4-bromostyryl acetate (1438389-19-5) + (Z)-4-bromostyryl acetate (1527491-72-0)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; stereoselective reaction; Inert atmosphere;

DOI:10.1002/cjoc.201800575

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + 4-Bromophenylboronic acid (5467-74-3) → (E)-4-bromostyryl acetate (1438389-19-5) + (Z)-4-bromostyryl acetate (1527491-72-0)

Guidance literature:

With palladium diacetate; p-benzoquinone; In acetic acid; dimethyl sulfoxide; at 60 ℃; for 12h; Time; Overall yield = 64 %; regioselective reaction;

DOI:10.1039/c3cc47045h

Reference yield:

4-bromophenethanol (4654-39-1) → (E)-4-bromostyryl acetate (1438389-19-5) + (Z)-4-bromostyryl acetate (1527491-72-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / dichloromethane / 3 h / 20 °C / Dean-Stark; Inert atmosphere

2: triethylamine / dichloromethane / 20 °C / Inert atmosphere

With sodium hydrogencarbonate; triethylamine; In dichloromethane;

DOI:10.1002/cjoc.201800575

upstream raw materials:

vinyl acetate

4-Bromophenylboronic acid

4-bromophenethanol

p-bromophenylacetaldehyde