2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol

Base Information

Chemical Name:2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol
CAS No.:5521-39-1
Molecular Formula:C12H19 N3 O
Molecular Weight:221.302
Hs Code.:2933599090
European Community (EC) Number:664-141-5
DSSTox Substance ID:DTXSID00354232
Wikidata:Q82132260
Mol file:5521-39-1.mol

Synonyms:5521-39-1;2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol;2-[4-(4-aminophenyl)piperazin-1-yl]ethanol;2-[4-(4-Amino-phenyl)-piperazin-1-yl]ethanol;1-piperazineethanol, 4-(4-aminophenyl)-;2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol;2-(4-(4-aminophenyl)piperazin-1-yl)ethan-1-ol;2-[4-(4-Amino-phenyl)-piperazin-1-yl]-ethanol;2-[4-(4-aminophenyl)-1-piperazinyl]-1-ethanol;Oprea1_328895;Oprea1_619019;SCHEMBL188852;DTXSID00354232;HCDBHFCQLBZAAZ-UHFFFAOYSA-N;BBL012623;MFCD00702247;STK347836;AKOS000104461;DS-13248;BB 0217040;CS-0157481;EU-0001180;FT-0681381;4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline;C75585;A870255;AG-690/10014060;2-[4-(4-AMINOPHENYL)PIPERAZINO]-1-ETHANOL

Suppliers and Price of 2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol
50mg
$ 110.00

SynQuest Laboratories
4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline
250 mg
$ 156.00

SynQuest Laboratories
4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline
100 mg
$ 98.00

Matrix Scientific
2-[4-(4-Aminophenyl)-1-piperazinyl]-1-ethanol
2.500g
$ 800.00

Matrix Scientific
2-[4-(4-Amino-phenyl)-piperazin-1-yl]-ethanol dihydrochloride
500mg
$ 170.00

Matrix Scientific
2-[4-(4-Aminophenyl)-1-piperazinyl]-1-ethanol
500mg
$ 250.00

Matrix Scientific
2-[4-(4-Aminophenyl)-1-piperazinyl]-1-ethanol
1g
$ 400.00

Matrix Scientific
2-[4-(4-Amino-phenyl)-piperazin-1-yl]-ethanol dihydrochloride
1g
$ 308.00

Crysdot
2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol 97%
1g
$ 253.00

Crysdot
2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol 97%
5g
$ 832.00

Total 20 raw suppliers

Chemical Property of 2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol

Chemical Property:

Vapor Pressure:2.28E-08mmHg at 25°C
Boiling Point:435.8°C at 760 mmHg
Flash Point:217.4°C
PSA：52.73000
Density:1.163g/cm³
LogP:0.96720
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:221.152812238
Heavy Atom Count:16
Complexity:196

Purity/Quality:

97% ^*data from raw suppliers

2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CCO)C2=CC=C(C=C2)N

Technology Process of 2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol

There total 6 articles about 2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 5521-38-0
2-(4-(4-nitrophenyl)piperazin-1-yl)ethan-1-ol

: 5521-39-1
2-(4-(4-aminophenyl)piperazin-1-yl)ethan-1-ol

Guidance literature:: With palladium on activated charcoal; In methanol; at 20 ℃;

Reference yield:

: 350-46-9,178603-76-4
4-Fluoronitrobenzene

: 5521-39-1
2-(4-(4-aminophenyl)piperazin-1-yl)ethan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-diisopropylethylamine / acetonitrile / 14 h / Heating

2: H₂ / Ra-Ni / tetrahydrofuran / 5 h / 20 °C / 2585.74 Torr

With hydrogen; N-ethyl-N,N-diisopropylamine; Ra-Ni; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm049355+

Reference yield:

: 103-76-4
1-(2-hydroxyethyl)piperazine

: 5521-39-1
2-(4-(4-aminophenyl)piperazin-1-yl)ethan-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 80 °C

2: hydrogen / palladium on activated charcoal / methanol / 2 h

With hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;