Technology Process of 4-chloro-7-nitro-1H-indazol-3-amine
There total 4 articles about 4-chloro-7-nitro-1H-indazol-3-amine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrazine hydrate;
In
ethanol;
at 15 - 25 ℃;
for 3h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sulfuric acid / 0.5 h / 0 - 15 °C / Large scale
1.2: 5 - 10 °C / Large scale
2.1: hydroxylamine hydrochloride / dimethyl sulfoxide / 3 h / 20 °C / Large scale
3.1: triethylamine / dichloromethane / 0.08 h / 0 - 5 °C / Large scale
3.2: 15 - 20 °C / Large scale
4.1: hydrazine hydrate / ethanol / 3 h / 15 - 25 °C
With
sulfuric acid; hydroxylamine hydrochloride; hydrazine hydrate; triethylamine;
In
ethanol; dichloromethane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydroxylamine hydrochloride / dimethyl sulfoxide / 3 h / 20 °C / Large scale
2.1: triethylamine / dichloromethane / 0.08 h / 0 - 5 °C / Large scale
2.2: 15 - 20 °C / Large scale
3.1: hydrazine hydrate / ethanol / 3 h / 15 - 25 °C
With
hydroxylamine hydrochloride; hydrazine hydrate; triethylamine;
In
ethanol; dichloromethane; dimethyl sulfoxide;
