C₂₃H₁₇ClF₅NO₄S

Base Information

• Chemical Name: C₂₃H₁₇ClF₅NO₄S
• CAS No.: 1426802-80-3
• Molecular Formula: C₂₃H₁₇ClF₅NO₄S
• Molecular Weight: 533.903
• Mol file: 1426802-80-3.mol

Synonyms:

Chemical Property of C₂₃H₁₇ClF₅NO₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₃H₁₇ClF₅NO₄S

There total 8 articles about C₂₃H₁₇ClF₅NO₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4,5-trifluoronitrobenzene (66684-58-0) → C23H17ClF5NO4S (1426802-80-3)

Guidance literature:

Multi-step reaction with 9 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 1.5 h / 0 - 20 °C / Inert atmosphere

1.2: 0 - 20 °C

2.1: acetic acid; sulfuric acid / water / 100 °C

3.1: palladium on activated charcoal; hydrogen / ethanol

4.1: hydrogenchloride; sodium nitrite / water / 0.75 h / 0 °C

4.2: 45 °C

4.3: pH 1

5.1: potassium hydroxide / 20 h / Reflux

6.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

7.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C

8.1: sodium hydroxide / water; ethanol / 20 °C

8.2: pH 1

9.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 20 °C

With hydrogenchloride; sulfuric acid; palladium on activated charcoal; hydrogen; sodium hydride; potassium carbonate; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-chloro-benzenecarboperoxoic acid; potassium hydroxide; sodium hydroxide; sodium nitrite; In ethanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

2-(2,6-difluoro-4-mercaptophenyl)acetic acid (1426805-34-6) → C23H17ClF5NO4S (1426802-80-3)

Guidance literature:

Multi-step reaction with 4 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C

3.1: sodium hydroxide / water; ethanol / 20 °C

3.2: pH 1

4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 20 °C

With potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-chloro-benzenecarboperoxoic acid; sodium hydroxide; In ethanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

2-(2,6-difluoro-4-nitrophenyl)malonate → C23H17ClF5NO4S (1426802-80-3)

Guidance literature:

Multi-step reaction with 8 steps

1.1: acetic acid; sulfuric acid / water / 100 °C

2.1: palladium on activated charcoal; hydrogen / ethanol

3.1: hydrogenchloride; sodium nitrite / water / 0.75 h / 0 °C

3.2: 45 °C

3.3: pH 1

4.1: potassium hydroxide / 20 h / Reflux

5.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C

6.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C

7.1: sodium hydroxide / water; ethanol / 20 °C

7.2: pH 1

8.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 20 °C

With hydrogenchloride; sulfuric acid; palladium on activated charcoal; hydrogen; potassium carbonate; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-chloro-benzenecarboperoxoic acid; potassium hydroxide; sodium hydroxide; sodium nitrite; In ethanol; dichloromethane; water; N,N-dimethyl-formamide;

upstream raw materials:

3,4,5-trifluoronitrobenzene

2-(2,6-difluoro-4-nitrophenyl)acetic acid

2-(4-amino-2,6-difluorophenyl)acetic acid

2-(4-((ethoxycarbonothioyl)thio)-2,6-difluorophenyl)acetic acid