(S)-1-(2-Furyl)-1-propanol

Base Information

• Chemical Name: (S)-1-(2-Furyl)-1-propanol
• CAS No.: 127418-31-9
• Molecular Formula: C₇H₁₀O₂
• Molecular Weight: 126.155
• UNII: 67S981UU1C
• Nikkaji Number: J563.495D
• Wikidata: Q27264154
• Mol file: 127418-31-9.mol

Synonyms:(S)-1-(2-Furyl)-1-propanol;2-(1-Hydroxypropyl)furan, (S)-;127418-31-9;(1S)-1-(furan-2-yl)propan-1-ol;UNII-67S981UU1C;67S981UU1C;2-Furanmethanol, alpha-ethyl-, (S)-;2-Furanmethanol, alpha-ethyl-, (alphaS)-;SCHEMBL7274806;(S)-2-(1-hydroxypropyl)furan;AKOS017361621;2-FURANMETHANOL, .ALPHA.-ETHYL-, (S)-;Q27264154;2-FURANMETHANOL, .ALPHA.-ETHYL-, (.ALPHA.S)-

Chemical Property of (S)-1-(2-Furyl)-1-propanol

Chemical Property:

• PSA: 33.37000
• LogP: 1.72300
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 126.068079557
• Heavy Atom Count: 9
• Complexity: 83

Purity/Quality:

(aS)-a-ethyl-2-Furanmethanol 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C1=CC=CO1)O
• Isomeric SMILES: CC[C@@H](C1=CC=CO1)O

Technology Process of (S)-1-(2-Furyl)-1-propanol

There total 31 articles about (S)-1-(2-Furyl)-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

furfural (98-01-1) + diethylzinc (557-20-0) → (S)-1-(2-furyl)propan-1-ol (127418-31-9)

Guidance literature:

furfural; diethylzinc; With (2S)-(?)-3-exo-(morpholino)isoborneol; In hexane; at 0 ℃; for 8h; Inert atmosphere;

With water; ammonium chloride; In hexane; optical yield given as %ee; enantioselective reaction;

DOI:10.1021/ol900905r

Reference yield: 94.0%

furfural (98-01-1) + ethyl bromide (74-96-4) → ethylfurfuryl alcohol (4208-61-1,119619-55-5,127418-31-9,128948-40-3)

Guidance literature:

ethyl bromide; With magnesium; In tetrahydrofuran; benzene; at 40 - 50 ℃; for 5h; Autoclave;

furfural; In tetrahydrofuran; benzene; at 8 - 10 ℃; for 7h;

Reference yield: 85.0%

furfural (98-01-1) + diethylzinc (557-20-0) → ethylfurfuryl alcohol (4208-61-1,119619-55-5,127418-31-9,128948-40-3)

Guidance literature:

furfural; diethylzinc; With C₃₀H₃₃NO₂P₂; In hexane; at -78 ℃; for 0.5h; Inert atmosphere;

at 20 ℃; for 1h; Reagent/catalyst;

DOI:10.1039/c4dt01789g

upstream raw materials:

furfural

diethylzinc

ethyl iodide

2-propionylfuran

Downstream raw materials:

ethyl 4-oxoheptanoate

2-ethyl-3-hydroxy-4-pyranone

6-hydroxy-2-ethyl-2H-pyran-3(6H)-one

(2S)-2-ethyl-6-hydroxy-2H-pyran-3(6H)-one