1-azabicyclo[2.2.2]oct-3-yl methanesulfonate

Base Information

Chemical Name:1-azabicyclo[2.2.2]oct-3-yl methanesulfonate
CAS No.:127424-06-0
Molecular Formula:C8H15NO3S
Molecular Weight:205.278
Hs Code.:
Mol file:127424-06-0.mol

Synonyms:3-[(methanesulfonyl)-oxy]-1-azabicyclo[2.2.2]octane;(+-) 3-Methanesulphonyloxy-1-azabicyclo[2.2.2]octane;3-methanesulfonyloxyquinuclidine;Methanesulfonic acid (S)-(1-aza-bicyclo[2.2.2]oct-3-yl) ester;3-Methanesulphonyloxy-1-azabicyclo[2.2.2]octane;

Suppliers and Price of 1-azabicyclo[2.2.2]oct-3-yl methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Quinuclidin-3-ylMethanesulfonate
5g
$ 510.00

TRC
Quinuclidin-3-ylMethanesulfonate
2.5g
$ 280.00

TRC
Quinuclidin-3-ylMethanesulfonate
500mg
$ 70.00

Total 2 raw suppliers

Chemical Property of 1-azabicyclo[2.2.2]oct-3-yl methanesulfonate

Chemical Property:

PSA：54.99000
LogP:1.07550

Purity/Quality:

99% ^*data from raw suppliers

Quinuclidin-3-ylMethanesulfonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Quinuclidin-3-yl Methanesulfonate is an intermediate is an intermediate in the synthesis of azoloazabicycloalkanes as cholinergic agonists.

Technology Process of 1-azabicyclo[2.2.2]oct-3-yl methanesulfonate

There total 1 articles about 1-azabicyclo[2.2.2]oct-3-yl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 124-63-0
methanesulfonyl chloride

: 1619-34-7
3-quinuclidinol

: 127424-06-0
3-<(methanesulfonyl)oxy>-1-azabicyclo<2.2.2>octane

Guidance literature:: With pyridine; In dichloromethane; 1.) 0 deg C, 20 min, 2.) RT, 1 h;
DOI:10.1021/jm00085a016 DOI:10.1021/jm00091a007

Reference yield:

: 127424-06-0
3-<(methanesulfonyl)oxy>-1-azabicyclo<2.2.2>octane

: 852469-94-4
3-(3-benzyloxy-4-phenylpyrazol-1-yl)-1-azabicyclo[2.2.2]octane

Guidance literature:: 3-benzyloxy-4-phenylpyrazole; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 20 - 50 ℃; for 0.75h;

3-<(methanesulfonyl)oxy>-1-azabicyclo<2.2.2>octane; In DMF (N,N-dimethyl-formamide); at 110 ℃; for 20h;

Reference yield:

: 127424-06-0
3-<(methanesulfonyl)oxy>-1-azabicyclo<2.2.2>octane

: 3-(3-Methoxy-4-phenylpyrazol-1-yl)-1-azabicyclo[2.2.2]-octane hydrochloride

Guidance literature:: 3-methoxy-4-phenylpyrazole; With potassium tert-butylate; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 1.5h;

3-<(methanesulfonyl)oxy>-1-azabicyclo<2.2.2>octane; In DMF (N,N-dimethyl-formamide); at 100 ℃; for 16h;